Adaptive and robust radiation therapy optimization for lung cancer Velibor V. Mišić Master of Applied Science Graduate Department of Mechanical and Industrial Engineering University of Toronto 2012 A previous approach to robust intensity-modulated radiation therapy (IMRT) treatment planning for moving tumours in the lung involves solving a single planning problem before treatment and using the ...

The purpose of this study is to get more efficient gold nanoparticles, for necrosis of cancer cells, in photothermal therapy. Therefore a numerical maximization of the absorption efficiency of a set of nanoparticles (nanorod, nanoshell and hollow nanosphere) is proposed, assuming that all the absorbed light is converted to heat. Two therapeutic cases (shallow and deep cancer) are considered. Th...

Cardiac resynchronization therapy is an established treatment modality in heart failure. Though non-response is a serious issue. To address this issue, a good understanding of the electrical activation during left bundle branch block, biventricular, as well as right- and left ventricular pacing is needed. This way by interpreting the 12-lead electrocardiogram, possible reasons for suboptimal tr...

Submit Manuscript | http://medcraveonline.com Abbreviations: TCP: Tumor Control Probability; NTCP: Normal Tissue Control Probability; LKB: Lyman Kutcher Burman; IGRT: Image Guided Radiation Therapy; IMRT: Intensity Modulated Radiation Therapy; SIB-IMRT: Simultaneous Integrated BoostIMRT; VMAT: Volumetric Modulated Arc Therapy; DA: Double Arc; SA: Single Arc; HT: Helical Tomotherapy; IFP: Improv...

In the Sochi sanatoriums, 609 patients with coronary heart disease, hypertensive disease, diabetes, metabolic syndrome and various combinations of these diseases were examined. The traditional and optimized medical complexes were used. The optimization implied the joining balneotherapy and climate therapy, therapeutic physical training and diet therapy, bioresonance therapy, “Magnerot” medicina...

Cardiac resynchronization therapy is an established treatment modality in heart failure. Though non-response is a serious issue. To address this issue, a good understanding of the electrical activation during underlying intrinsic ventricular activation, biventricular as well as right- and left ventricular pacing is needed. By interpreting the 12-lead electrocardiogram, possible reasons for subo...

Approximately one third of patients treated with cardiac resynchronization therapy do not derive any detectable benefit. In these patients, acute invasive hemodynamic evaluation can be used for therapy optimization. This report describes the use of systematic invasive hemodynamic measurements for clinical decision making in a patient who experienced severe ventricular arrhythmias and clinical d...