Candida spp. are common causes of bloodstream infections among hospitalized patients. Fluconazole (FLC) remains a first-line therapy for candidemia; and voriconazole (VRC), an expanded-spectrum triazole, was recently approved for the treatment of candidemia in nonneutropenic patients. In vitro studies have suggested that VRC has potent activity against Candida spp. with reduced susceptibilities...

BACKGROUND: Oropharyngeal candidiasis is a common infection in patient receiving radiotherapy for head and neck cancer. Accurate and rapid identification of candida species is very important in clinical laboratory, because the incidence of candidiasis continues to rise after radiotherapy. The genus Candida has about 154 species that show different level of resistance to antifungal drugs and hav...

regarding the importance of bacillus thuringiensisisolates in microbial control, we attempted to collect native isolates and study their virulence on diamondback moth, plutella xylostella. more than 148 samples were collected from guilan, mazandaran, west azarbaijan and alborz provinces. experimental samples including soil samples from forest, fruit gardens, agricultural fields, diseased and de...

background candida species are normal microflora of  oral cavity, vagina, and gastrointestinal  tract. they are the third most prevalent cause of pediatric health care–associated  bloodstream fungal infection. this study aimed to provide an epidemiological feature of candidiasis and also presents an antifungal susceptibility profile of clinical candida isolates among children. materials and met...

Recently, numerous cases of dermatophytosis resistant to terbinafine were reported. These have been increasing in frequency, with no improvement even treatment using systemic therapies. Our objective was determine the antifungal activity efinaconazole compared fluconazole, itraconazole, and against dermatophyte, Candida, mold clinical isolates In vitro. Activity antifungals assessed minimum inh...

background and purpose: oropharyngeal candidiasis (opc) and antifungal drug resistance are major health concerns in patients with human immunodeficiency virus (hiv). the increased reports of antifungal resistance and expanding drug therapy options prompted the determination of antifungal susceptibility profile. the present study was performed to determine the antifungal susceptibility of candid...

Abstract Mycotoxins, the metabolites of toxigenic fungi are important contaminants food and agriculture industry throughout world. Among different strategies to minimize mycotoxins synthesis decontamination food; yeasts their derivatives used as efficient biological control agents. In this study, cell walls (CW) six yeast strains; two commercial baking {Saccharomyces cerevisiae (Sc 1 Sc2)}, low...

Introduction: Acne is a pathological disorder and a chronic inflammation in the sebaceous follicles, and one of the most popular dermatology damages that has affected millions of people worldwide. The aim of this study was to identify Candida species in patients with acne as well as determine the drug susceptibility of these species.   Materials & Methods: In this cross-sectional study, 70 cl...

The frequency of fungal infections in immunocompromised patients, particularly by Candida species, has increased in recent years. Colonization by Candida species in respiratory tract in susceptible hosts may play an important role to precede disseminated candidiasis. This study was designed to identify Candida species from bronchoalveolar lavage (BAL) samples and determination of antifungal sus...

Denture stomatitis is an inflammatory condition that occurs in denture wearers and is frequently associated with Candida yeasts. Antifungal susceptibility profiles have been extensively evaluated for candidiasis patients or immunosupressed individuals, but not for healthy Candida carriers. In the present study, fluconazole, itraconazole, voriconazole, terbinafine and 5-flucytosin were tested ag...