In patients with chronic coronary artery disease and left ventricular dysfunction, the distinction between ventricular dysfunction arising from myocardial fibrosis and ischemic, but viable, myocardium has important clinical implications. By positron emission tomography (PET), enhanced fluorine-18-labeled fluorodeoxyglucose (FDG) uptake in myocardial segments with impaired function and reduced b...

Background: The incorporation of thallium-201 into 8-hydroxyquinoline was targeted for cell labeling due to interesting physical properties and wide availability of this nuclide as a single photon emission computed tomography (SPECT) radionuclide. Materials and Methods: Thallium-201 (T1/2=3.04 d) in Tl+ form was converted to Tl3+ cation in presence of O3/6M HCl and di-isopropyl ether, controlle...

OBJECTIVES The purpose of the study was to evaluate the relationship between elevated lung/heart ratio (LHR) and transient ischemic dilation (TID) after stress thallium-201 myocardial perfusion imaging and to provide further insight into the mechanism of cavity dilation. BACKGROUND Because both LHR and TID have been identified as adjunctive markers of severe coronary disease they should be fo...

Fifty-two patients with suspected coronary artery disease underwent coronary angiography, thallium-201 myocardial imaging, and ECG-gated blood pool ventriculography at rest and at maximal exercise. In 11 patients without coronary artery disease, all thallium images were normal. The resting ejection fraction (EF) was normal in all 11 patients and increased during exercise in six, was unchanged i...