ammalian sex-determining factors with homology to DNA binding proteins are required for splicing, according to a study by Paolo SassoneCorsi and coworkers at the Université Louis Pasteur (Strasbourg, France). Examination of high mobility group (HMG) domain containing SRY and Sox proteins demonstrated a surprising but clear association with splicing complexes. SRY, the testis-determining factor ...

Understanding origin, evolution and functions of small RNA (sRNA) genes has been a great challenge in the past decade. Molecular mechanisms underlying sexual reversal in vertebrates, particularly sRNAs involved in this process, are largely unknown. By deep-sequencing of small RNA transcriptomes in combination with genomic analysis, we identified a large amount of piRNAs and miRNAs including ove...

Sex differentiation of gonads in amphibians is believed to be controlled genetically, but altered epigenetically or environmentally. When larvae of the salamander Hynobius retardatus were reared at defined temperatures from hatching to metamorphic stages, a high temperature (28 degrees C) induced exclusively female gonads (ovaries), whereas intermediate (20 and 23 degrees C) or lower (16 degree...

Traditionally, testosterone and estrogen have been considered to be male and female sex hormones, respectively. However, estradiol, the predominant form of estrogen, also plays a critical role in male sexual function. Estradiol in men is essential for modulating libido, erectile function, and spermatogenesis. Estrogen receptors, as well as aromatase, the enzyme that converts testosterone to est...

Swyer syndrome is also known as complete/pure gonadal dysgenesis & associated with an absence of testicular differentiation in a phenotypic female 46, XY karyotype. A 23-year-old married girl had come complaints primary infertility. She was averagely built nourished. well developed secondary sexual characteristics like breast development, axillary hairs, and pubic hairs (Tanners stage 4) to...

Cochicó belongs to “Encadenadas del Oeste” system of lakes being a typical water body the Pampas region. The most abundant fish species in this lake is pejerrey (Odontesthes bonariensis) valued due quality its flesh and as game fish. aim study was compare gonadal stages during two consecutive spawning seasons (August December) relation sexual steroids temperature lake. In general, development, ...

It is now well established that the differentiation of the primitive gonad into the testis during early human embryonic development depends on the presence of the SRY gene. However, the existence of total or partial sex reversal in 46,XX males with genetic mutations not linked to the Y chromosome suggests that several autosomal genes acting in association with SRY may contribute to normal devel...

BACKGROUND Interpersonal sensitivity is characterized by the predisposition to perceive and elicit criticism, rejection, and negative social evaluation. It may be linked to poorer physical or functional health outcomes, particularly in the interpersonal context (cancer-related sexual dysfunction). PURPOSE This study tested the association of interpersonal sensitivity with sexual functioning f...

BACKGROUND This study was conducted to determine if serum inhibin B concentration can predict spermatogenesis in azoospermic infertile men. METHODS This cross-sectional study included 70 patients with male-factor infertility referred to Alvand and Vali-e-Asr Infertility Centers, Tehran, Iran. All patients had azoospermia. Standard evaluation consisted of history and physical examination with ...