نتایج جستجو برای: taqi modarresi

تعداد نتایج: 713  

Journal: :The Tohoku journal of experimental medicine 2012
Duygu Gezen-Ak Erdinç Dursun Basar Bilgiç Hasmet Hanağasi Turan Ertan Hakan Gürvit Murat Emre Engin Eker Turgut Ulutin Omer Uysal Selma Yilmazer

Vitamin D(3) is a neurosteroid that mediates its effects via the vitamin D receptor (VDR). The VDR gene is located on chromosome 12q13 and consists of 9 exons. VDR contains the DNA-binding site encoded by exons 2 and 3 and the ligand-binding site encoded by exons 4 - 9. Our earlier study showed that the ApaI polymorphic site of the VDR gene is associated with late-onset Alzheimer's disease (...

ژورنال: پژوهش در پزشکی 2005
فریدون عزیزی, , مریم السادات دانشپور, , مهدی هدایتی, ,

Background: The aim of this study was to examine whether the well established effect of the common TaqI polymorphism in CETP gene on HDL-C concentration could be explained by the recently identified -629A/C functional polymorphism in the promoter. Material and method: To examine the association between A allele and HDL-C level, 943 healthy subjects enrolled in TLGS study were selected, among w...

Journal: :Indian journal of experimental biology 2009
Sangeeta Dalal Gaya Prasad Minakshi Prasad Sushila Maan

The genome segment 7 of two Indian isolates of bluetongue virus (BTV) from Avikanagar (BTV-1-western India) and Hyderabad (BTV-Untyped Hyderabad-southern India) was amplified by RT-PCR using two sets of VP7 specific primers. A sequence of 1137 bp comprising the complete coding sequence of the VP7 gene from Avikanagar isolate and a 1154 bp full-length sequence from BTV-UT Hyderabad isolate were ...

2013
Fang Wu Wanjiang Zhang Le Zhang Jiangdong Wu Chunzhu Li Xianjie Meng Xi Wang Peng He Jie Zhang

BACKGROUND To explore the potential role of natural-resistance-associated macrophage protein 1 (NRAMP1) gene, vitamin D receptor (VDR) gene, (human leukocyte antigen, (HLA-DRB1) HLA)-DRB1 gene, and HLA-DQB1 gene polymorphisms in susceptibility to tuberculosis (TB) in the Chinese Kazakh population. METHODS A case-control study was performed on the Chinese Kazak population. Genetic polymorphism...

Journal: :Nucleic acids research 1990
D P Bouvier S H Chen A R Thompson

A factor IX polymorphism 5' to exon 2 was described as 1.70 versus 1.75 kb bands on Southern blots of Ddel digests (1). By primer directed polymerase chain reaction (PCR) amplification, the two alleles are readily apparent on agarose electrophoresis of undigested fragments (430 or 380 bp); in heterozygous women or amplified mixtures of two hemizygous male types, an additional fragment (~480 bp)...

Journal: :Urologia internationalis 2011
Yiwei Lin Qiqi Mao Xiangyi Zheng Hong Chen Kai Yang Liping Xie

OBJECTIVE Genetic variants of vitamin D receptor (VDR) were implicated in urolithiasis susceptibility in several case-control studies. However, these studies so far have provided conflicting results. In order to investigate the potential relationship, a meta-analysis was conducted. METHODS Eligible studies were retrieved via both computerized searches and review of references. The relation of...

2013
Xing Yao Huazong Zeng Guolei Zhang Weimin Zhou Qiang Yan Licheng Dai Xiang Wang

AIM To evaluate the possible association between the vitamin D receptor (VDR), single-nucleotide polymorphisms (SNPs), and hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV) infection. METHOD 968 chronic HBV infection patients were enrolled, of which 436 patients were diagnosed HCC patients, and 532 were non-HCC patients. The clinicopathological characteristics of...

2018
Letícia de Paula Scalioni Betânia Rodrigues dos Santos Poli Mara Spritzer Cristiane Alves Villela-Nogueira Lia Laura Lewis-Ximenez Priscila Pollo-Flores Eliane Bordalo Cathalá Esberard Carlos Eduardo Brandão-Mello Elisabeth Lampe Livia Melo Villar

Potential relationship of vitamin D, vitamin D receptor (VDR), and vitamin D binding protein (DBP) have been suggested in the pathophysiology of hepatitis C virus (HCV) infection. The aim of this observational study is to determine vitamin D levels, and VDR and DBP genetic polymorphism according demographic and laboratory data in chronic HCV patients (CHC).A total of 148 CHC patients gave serum...

Journal: :Bone 2009
Asma Arabi Laila Zahed Ziyad Mahfoud Lina El-Onsi Mona Nabulsi Joyce Maalouf Ghada El-Hajj Fuleihan

OBJECTIVES Vitamin D receptor (VDR) gene plays an important role in bone mass regulation. We have previously shown a beneficial effect of vitamin D supplementation on bone mass in girls. This study investigated whether the musculo-skeletal response to Vitamin D was modulated by polymorphisms in VDR gene. DESIGN Randomized placebo-controlled trial. METHODS 179 girls (10-17 years), were rando...

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