نتایج جستجو برای: tanshinone iia sodium

تعداد نتایج: 196391  

Journal: :Molecules 2015
Jian-Ping Dai Dan-Xia Zhu Jiang-Tao Sheng Xiao-Xuan Chen Wei-Zhong Li Ge-Fei Wang Kang-Sheng Li Yun Su

Salvia miltiorrhiza Bunge has been reported to possess excellent antifibrotic activity. In this study, we have investigated the effect and mechanism of tanshinone IIA (Tan-IIA), salvianolic acid A (Sal-A) and salvianolic acid B (Sal-B), the important active compounds of Salvia miltiorrhiza Bunge, on areca nut extract (ANE)-induced oral submucous fibrosis (OSF) in vitro. Through human procollage...

Journal: :The Journal of surgical research 2012
Tao Shang Zhao Liu Min Zhou Christopher K Zarins Chengpei Xu Chang-jian Liu

BACKGROUND The purpose of the present study was to investigate whether tanshinone IIA (Tan IIA), one of the major lipophilic components of Salvia miltiorrhiza Bunge, could inhibit the development of elastase-induced experimental abdominal aortic aneurysms (AAAs). METHODS Male Sprague-Dawley rats (n = 12/group) were randomly distributed into three groups: Tan IIA, control, and sham. The rats f...

Journal: :Molecules 2012
Yingjie Wei Ping Li Changmei Wang Yunru Peng Luan Shu Xiaobin Jia Wenquan Ma Bing Wang

The study aimed to investigate the potential of zebrafish in imitating mammal phase I metabolism of natural compounds. Three diterpenoid quinones from Radix Salvia miltiorrhiza, namely tanshinone IIA (TIIA), cryptotanshinone (Cry) and tanshinone I (TI) were selected as model compounds, and their metabolites mediated by zebrafish were characterized using a high-performance liquid chromatography ...

Journal: :Evidence-Based Complementary and Alternative Medicine 2011

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