We demonstrated how the special synergy between a noble metal single site and neighboring oxygen vacancies provides an “ensemble reaction pool” for high hydrogen generation efficiency carbon dioxide (CO2) selectivity of tandem reaction: methanol steam reforming. Specifically, rate over Ru1/CeO2 catalyst is up to 9360 mol H2 per Ru hour (579 mLH2 gRu–1 s–1) with 99.5% CO2 selectivity. Reaction m...

We report a detailed synthetic and mechanistic study of an unusual bifunctional, sequential hetero-Diels-Alder/ring-opening reaction in which chiral, metal complexed ketene enolates react with o-quinones to afford highly enantioenriched, alpha-hydroxylated carbonyl derivatives in excellent yield. A number of Lewis acids were screened in tandem with cinchona alkaloid derivatives; surprisingly, t...

According to the strong application background of bioflavonoid and metal-flavonoid complexes, novel electrospray ionization tandem mass spectrometry (ESI-MSn) was applied to investigate the structure and fragmentation mechanism of transition metal-rutin complexes. In the full-scan mass spectra, different stoichiometric ratios of rutin-metal complexes were found. In the reaction between rutin an...

Complex natural products are a proven and rich source of disease-modulating drugs and of efficient tools for the study of chemical biology and drug discovery. The architectures of complex natural products are generally considered to represent significant barriers to efficient chemical synthesis. Here we describe a concise and efficient asymmetric synthesis of 19-dehydroxyl arisandilactone A-whi...

Reaction monitoring by electrospray (ESI) mass spectrometry (MS) is a valuable technique to investigate reaction mechanisms. It allows glimpse into the reacting solution and characterization of transient intermediates tandem spectrometry. Herein we studied an intriguing gold(III)-catalyzed synthesis dicoumarins which includes combination hydroarylation homocoupling steps. Reactants products cou...

Abstract A novel and sustainable tandem‐catalysis system for asymmetric synthesis is disclosed, which fabricated by bio‐inspired self‐assembly of artificial arthropod exoskeletons (AAE s) or fungi cell walls ( AFCW containing two different types catalysts (enzyme metal nanoparticles). The heterogeneous integrated enzyme/metal nanoparticle AAE / systems, contain chitosan as the main structural c...

background : fms-like tyrosine kinase 3 is a tyrosine kinase receptor that plays an important role in proliferation and differentiation of hematopoietic stem cells. internal tandem duplication and tyrosine kinase domain mutation are the two most common types of fms-like tyrosine kinase 3 mutations frequently reported in acute myeloid leukemia associated with pathogenesis of this disease. the pr...

A Cu-catalyzed tandem dehydrogenation/dehalogenation sequential reaction along with N-arylation has been developed for the synthesis of pyridazinone derivatives in an aerobic and aqueous environment. To achieve the transformation of three chemical bonds in a one-pot reaction, a multifunctional copper catalyst was used which afforded excellent activity, high selectivity, and recyclability. The c...

Angular distribution of the 12C(7Li,6He)13N reaction at E(7Li) = 44.0 MeV was measured at the HI-13 tandem accelerator of Beijing, China. Asymptotic normalization coefficient (ANC) of 13N → 12C + p was derived to be 1.64 ± 0.11 fm−1/2 through distorted wave Born approximation (DWBA) analysis. The ANC was then used to deduce the astrophysical S(E) factors and reaction rates for direct capture in...

A metal-free tandem reaction, initiated by the generation of a diazonium cation and followed by cycloetherification, was developed. Acid-promoted de-tert-butylation of N-nitroso N-tert-butylamine was used to generate a diazonium cation in situ, demonstrating a new application of nitroso chemistry. This reaction was employed in the synthesis of substituted benzofuran-3(2H)-ones and dihydrobenzo[...