Using 50 percent growth inhibition of Physarum polycephalum (a coenocytic slime mold) as a screen for the selection of antitumor agents, 44 of the 195 compounds tested were effective at concentrations of@lOO @tg/m1. Results of inhibition of KB cell cul ture screen are given for comparison. INTRODUCTION Physanun polycephalum can be grown in a surface culture as a large, multinucleate plasmodium ...
