Tanshinone IIA (Tan-IIA) is an extract from the widely used traditional Chinese medicine (TCM) Danshen (Salvia miltiorrhiza), and has been found to attenuate the proliferation of bladder cancer (BCa) cells (The IC50 were: 5637, 2.6 μg/mL; BFTC, 2 μg/mL; T24, 2.7 μg/mL, respectively.). However, the mechanism of the effect of Tan-IIA on migration inhibition of BCa cells remains unclear. This stud...

We examined the role of the sarcolemmal and mitochondrial ATP-sensitive potassium (K(ATP)) channel in a rat model of myocardial infarction after stimulation with the selective delta(1)-opioid receptor agonist TAN-67. Hearts were subjected to 30 min of regional ischemia and 2 h of reperfusion. Infarct size was expressed as a percentage of the area at risk. TAN-67 significantly reduced infarct si...

A bicycle (n, k)-gon is an equilateral n-gon whose k-diagonals are equal. S. Tabachnikov proved that a regular n-gon is first-order flexible as a bicycle (n, k)-gon if and only if there is an integer 2 ≤ r ≤ n − 2 such that tan(π/n) tan(krπ/n) = tan(kπ/n) tan(rπ/n). In the present paper, we solve this trigonometric diophantine equation. In particular, we describe the family of first order flexi...

1 Department o f Animal Nutr i t ion, Universi ty of Veter inary and Animal Sc iences, Lahore, 2 Department o f Ther iogeno logy, Facul ty o f Veter inary Sciences, Bahauddin Zakar iya Univers i ty, Mul tan, Pakis tan 3 Department o f Patho logy, Arid Agr icul ture Univers i ty, Rawalp indi , Pakis tan 4 Department o f Basic Sciences, Sub campus Jhang, Univers i ty o f Veter inary and Animal Sc...

Seven heart regulatory neurones (PON, TAN, TAN-2, TAN-3, d-RCDN, d-LCDN and VG1) were identified in the central nervous system of the African giant snail, Achatina fulica Ferussac. Among these neurones, the periodically oscillating neurone (PON) was the most effective heart excitor, producing heart excitation at rather low firing frequencies. The tonically autoactive neurones (TAN, TAN-2 and TA...

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Intercalation of Ba in β-FeSe by ammonothermal synthesis results in the formation of different superconducting phases with interlayer distance ranging between 8.4 and 13.1 Å. The values of Tc are primarily dependent on Ba content, and are further modulated by the interlayer spacing through facile intercalation and deintercalation of ammonia.