نتایج جستجو برای: tac

تعداد نتایج: 5005  

Journal: :Annals of the rheumatic diseases 2000
J C Morris T A Waldmann

T cell activation and cellular immune responses are modulated by interleukin 2 (IL2) through binding to its corresponding cell surface receptor. Three forms of the receptor are recognised based on IL2 binding affinity. The high affinity receptor is a heterotrimer composed of alpha, beta, and gamma(c)-polypeptide chains. The 55 kDa alpha-chain also known as the Tac (T cell activation) antigen or...

Journal: :Circulation 2008
Xavier Loyer Ana Maria Gómez Paul Milliez Maria Fernandez-Velasco Peter Vangheluwe Laurent Vinet Dominique Charue Emilie Vaudin Wei Zhang Yannis Sainte-Marie Estelle Robidel Isabelle Marty Bernd Mayer Frédéric Jaisser Jean-Jacques Mercadier Sylvain Richard Ajay M Shah Jean-Pierre Bénitah Jane-Lise Samuel Christophe Heymes

BACKGROUND Defects in cardiomyocyte Ca(2+) cycling are a signature feature of heart failure (HF) that occurs in response to sustained hemodynamic overload, and they largely account for contractile dysfunction. Neuronal nitric oxide synthase (NOS1) influences myocyte excitation-contraction coupling through modulation of Ca(2+) cycling, but the potential relevance of this in HF is unknown. METH...

Journal: :Acta scientiarum polonorum. Technologia alimentaria 2012
Dorota Martysiak-Żurowska Weronika Wenta

INTRODUCTION The Total Antioxidant Capacity (TAC) of human milk reflects the concentration and the activity of many components which prevent oxidative degradation of fats and proteins. This study compares the effectiveness of ABTS and DPPH tests with regard to the recovery, precision and sensitivity (detection and quantification limit) of (TAC) values in human milk. MATERIAL AND METHODS TAC v...

2014
Yin-Yu Chang Heng-Li Huang Ya-Chi Chen Jui-Ting Hsu Tzong-Ming Shieh Ming-Tzu Tsai

Tantalum (Ta) is a promising metal for biomedical implants or implant coating for orthopedic and dental applications because of its excellent corrosion resistance, fracture toughness, and biocompatibility. This study synthesizes biocompatible tantalum carbide (TaC) and TaC/amorphous carbon (a-C) coatings with different carbon contents by using a twin-gun magnetron sputtering system to improve t...

2015
Yi Li Lin Yan Yunying Shi Yangjuan Bai Jiangtao Tang Lanlan Wang

CYP3A5 and ABCB1 polymorphisms have been shown to influence tacrolimus blood concentrations and dose requirements, but the conclusion in the current reports were inconformity. Sirolimus are also metabolized by CYP3A subfamily and are substrates of the P-gp. The aim was to determine whether these polymorphisms affect tacrolimus (TAC) and sirolimus (SRL) trough concentrations and dose requirement...

Journal: :AI Commun. 2006
Joakim Eriksson Niclas Finne Sverker Janson

TAC SCM is a supply chain management game for the Trading Agent Competition (TAC). The purpose of TAC is to spur high quality research into realistic trading agent problems. We discuss TAC and TAC SCM: game and competition design, scientific impact, and lessons learnt. With a conscious effort to these ends, a competition may help focus research on well-chosen problems in high impact domains, fa...

Journal: :Molecules 2011
Darko Duplancic Lea Kukoc-Modun Darko Modun Njegomir Radic

Determination of the relative contribution of uric acid level increases to the total measured antioxidative activity could be very useful for testing antioxidative products and their effect on human health. The aim of this report is to present a simple spectrophotometric method that combines the measurement of total antioxidative capacity of a sample by ferric reducing/antioxidative power (FRAP...

Journal: :Clinical and Experimental Health Sciences 2021

Objective: Cyclosporine A (CsA) and tacrolimus (Tac) are immunosuppressive drugs which is frequently used in organ transplantation. CsA can cause various side effects including gingival overgrowth (GO) osteopenia. Tac has similar to but with different incidences. The aim of the present study was evaluate compare on GO alveolar bone resorption rats.
 Methods: Sixty mature male rats were ran...

2011
Jae-Hyung Lee Christopher Greer Shuxun Ren Yibin Wang Xinshu Xiao

RNA purification, library preparation and Illumina sequencing Left ventricular tissues were collected from male C57BL/6 mice after 1 week (hypertrophy stage, HY) and 8 weeks post trans-aortic constriction (TAC) procedure (heart failure stage, HF), respectively, and their corresponding Sham controls (Sham-HY, Sham-HF). Doppler velocity measurements of right and left carotid arteries were obtaine...

2008
David J. Chess Wenhong Xu Ramzi Khairallah Karen M. O’Shea Willem J. Kop Agnes M. Azimzadeh William C. Stanley

Chess DJ, Xu W, Khairallah R, O’Shea KM, Kop WJ, Azimzadeh AM, Stanley WC. The antioxidant tempol attenuates pressure overload-induced cardiac hypertrophy and contractile dysfunction in mice fed a high-fructose diet. Am J Physiol Heart Circ Physiol 295: H2223–H2230, 2008; doi:10.1152/ajpheart.00563.2008.—We have previously shown that high-sugar diets increase mortality and left ventricular (LV)...

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