lupus erythematosus (le) is an autoimmune disease. the mortality rate and causes of death are different in various countries. the present study is done to find out the causes of mortality in the systemic lupus erythematosus (sle) patients in lupus unit of rheumatology research center and other wards of shariati hospital. this study was retrospective according to medical records of patients who ...

This is a rare case report of systemic allergic reaction to fish allergen ingested through breast milk. Mother ate raw fish more than 3 times a week. Her consumption of fish was associated with urticaria and wheeze in an infant via breast-feeding. Fish-specific IgE antibodies were detected by skin prick test but not by in vitro IgE test. This case demonstrates that fish protein ingested by moth...

The purpose of diagnostic procedure is to classify a sting reaction by history, identify the underlying pathogenetic mechanism, and identify the offending insect. Diagnosis of Hymenoptera venom allergy thus forms the basis for the treatment. In the central and northern Europe vespid (mainly Vespula spp.) and honeybee stings are the most prevalent, whereas in the Mediterranean area stings from P...

Sir, Paraneoplastic syndromes are defined as nonmetastatic systemic effects that accompany malignant disease. These syndromes may occur in up to 10-15% of malignancies. A few paraneoplastic syndromes have been reported in metastatic transitional cell carcinoma including hypercalcemia, thrombocytosis, eosinophilia, nephrotic syndrome, acanthosis nigricans, dermatomyositis, polymyositis, and leuk...

A 67-yr-old female patient gave a history of allergy to lignocaine. When she was challenge-tested with the intradermal injection of 0.5% bupivacaine 0.2ml she had a systemic reaction. This reaction was accompanied by a decrease in the concentration of complement C4 in the plasma, which indicated that the reaction was immunologically-mediated. This is the first report of allergy to a local anaes...

Wasp stings are ubiquitous worldwide and generally cause self-limiting local reaction. Occasionally more serious systemic reactions such as anaphylaxis, rhabdomyolysis, and intravascular hemolysis may occur, especially with multiple stings. Although exceedingly rare, neurologic complications of the wasp sting have been described. We report a case of allergic encephalitis with gelastic status ep...

Sir, Chemotherapy-induced acral erythema (CIAE) is a cytotoxic drug reaction to certain systemic chemotherapeutic agents, such as £uorouracil, doxorubicin, and especially cytosine arabinoside (1). Following discontinuation of chemotherapy, cutaneous lesions subside in 1 ^ 2 weeks with eventual desquamation. Rechallenge of patients with similar chemotherapeutic agents has reproduced the reaction...

Aprotinin is widely used to prevent bleeding, inhibit systemic inflammatory response and reduce blood transfusions after cardiac surgery. Because it is a bovine protein, aprotinin can induce hypersensitivity reactions. We report a case of fatal anaphylactoid reaction to primary aprotinin exposure in a woman who was admitted for mitral valve replacement. The possibility of anaphylactic reaction ...

this paper describes one university’s approach to improving the quality of teaching and learning at the institutional level, based on the premise of improving the design of curriculum rather than focusing on the skills of teachers as such. the paper describes the process by which university-wide principles of curriculum design were defined and agreed, as well as the parallel campaigns needed to...

Systemic lupus erythematosus is a severe inflammatory connective tissue disease induced by autoimmunity. The cytochrome p450 27B1 gene, activating Vitamin D precursor 25-hydroxyvitamin into 1,25-dihydroxyvitamin in immunity cells resulted autoimmune disorders. This study was assessing the correlation and clinical pathological characteristics relationship between gene polymorphism rs10877012/rs4...