The Streptococcus pneumoniae ComDE two-component signaling system controls the development of genetic competence in the bacterium and affects virulence in models of pneumonia and bacteremia. We have investigated the impact of the competence pathway during colonization of the nasopharynx, the principal ecological niche of the pneumococcus. Previous work showed that deletion of the pneumococcal C...

This is a study of the course of the conduction system in two cases of hypoplasia of the aortic tract complex, one with mitral stenosis and the other with mitral atresia. In both there was a posterior atrioventricular (AV) node which formed the AV bundle. In case 1 the bundle was short and bifurcated early. The branching bundle gave off a large left bundle branch (LBB), many Mahaim fibers to th...

Previously, we proposed a speaker recognition system using a combination of MFCC-based vocal tract feature and phase information which includes rich vocal source information. In this paper, we investigate the efficiency of combination of various vocal tract features (MFCC and LPCC) and vocal source features (phase and LPC residual) for normal-duration and short-duration utterance. The Japanese ...

One of the hallmarks of urinary tract infection, a serious global disease, is its tendency to recur. Uropathogenic bacteria can invade cells lining the bladder, where they form longer-term intracellular reservoirs shielded from antibiotics, re-emerging at a later date to initiate flare-ups. In these cases, only lengthy systemic antibiotic treatment can eradicate all the reservoirs. Yet, long co...

We propose methods to track natural variations in the characteristics of the vocal-tract system from speech signals. We are especially interested in the cases where these characteristics vary over time, as happens in dynamic sounds such as consonant-vowel transitions. We show that the selection of appropriate analysis segments is crucial in these methods, and we propose a selection based on est...

Inflammatory myofibroblastic tumor (IMT) rarely arises in genitourinary tract especially beyond collecting system, which determines the unspecific clinic symptoms and sometimes can mimic malignancy. Therefore, IMT's diagnosis may usually be a pitfall. This case report characterizes a 35-year-old woman with a history of lower quadrant lasting pain followed by fever. Furthermore, radiologic exami...

Careful clinical and investigative protocols allow the identification of a homogeneous group of patients with prostatodynia or 'anxious bladder syndrome' (underactive detrusor function). Psychophysiological studies and urodynamic measurements in such patients demonstrate remarkably consistent results, which, whilst lending support to the hypothesis that the sympathetic nervous system may effect...

The acoustic wave propagation inside the vocal tract was simulated assuming plane waves. When an acoustic tube having appropriate area function but no side branching cavities was used as the nasal tract, the low frequency nasal formant below the first formant of low vowels as observed in natural speech could not be simulated. The relatively short nasal tract with both ends open cannot produce t...

Idiopathic outflow tract ventricular arrhythmias (VAs) represent a significant proportion of all VAs. The mechanism is thought to be catecholamine-mediated delayed after depolarizations and triggered activity, although other etiologies should be considered. In the adult cardiac conduction system it has been demonstrated that sometimes an embryonic branch, the so-called "dead-end tract", persist...

Perception of speaker identity is an important characteristic of the human auditory system. This paper describes a subjective test for the investigation of the relevance of four acoustic features in this process: vocal tract, pitch, duration, and energy. PSOLA based methods provide the framework for the transplantations of these acoustic features between two speakers. The test database consists...