The major arteries and veins of the vertebrate circulatory system are formed early in embryonic development, before the onset of circulation, following de novo aggregation of "angioblast" progenitors in a process called vasculogenesis. Initial embryonic determination of artery or vein identity is regulated by variety of genetic factors that work in concert to specify endothelial cell fate, givi...

The challenge of treating older, obese patients with various comorbidities has become a mainstay of anesthetic practice. In order to monitor and provide anesthesia safely, the nurse anesthetist must weigh the risks and benefits of all types of monitoring when these patients undergo major invasive procedures. One such option is the Swan-Ganz pulmonary artery catheter. During the last decade an e...

This article reports the findings of a study developed to compare health care costs in the United States with those of eight other industrially advanced countries over the period 1960-76. All of the countries studied were found to share with the United States the problem of increased health care spending that has outpaced inflation in other sectors of the economy and continues to consume a grow...

BACKGROUND Segregation of the trophectoderm from the inner cell mass of the embryo represents the first cell-fate decision of mammalian development. Transcription factors essential for specifying trophectoderm have been identified, but the role of microRNAs (miRNAs) in modulating this fate-choice has been largely unexplored. We have compared miRNA expression in embryonic stem cell (ESC)-derived...

This article reports the findings of a study developed to compare health care costs in the United States with those of eight other industrially advanced countries over the period 1960-76. All of the countries studied were found to share with the United States the problem of increased health care spending that has outpaced inflation in other sectors of the economy and continues to consume a grow...

OBJECTIVE To describe a patient who presented with nonfixed swan neck deformity of the fingers and generalized body aches. DESIGN Case report. SETTING Tertiary care teaching hospital. PATIENT A 38-year-old woman who presented with swan neck deformity of the fingers. MAIN OUTCOME MEASURES Electromyographic finding and electromyographic and clinical response to intravenous immunoglobulin....

The purpose of our study was to determine whether self-reported physical activity (PA), including recreational, household, and exercise activities, is associated with intra-abdominal fat (IAF) in community-dwelling white and black midlife women. We performed a cross-sectional study of 369 women from the Chicago site of the Study of Women's Health Across the Nation (SWAN) ancillary study, the SW...