Sir, Campylobacter macrolide resistance can involve an efflux mechanism. This mechanism was evidenced by the restoration of bacterial susceptibility after addition of phenylalanine-arginine b-naphthylamide (PAbN), an efflux pump inhibitor, in the culture medium. In this study we wanted to determine the prevalence of macrolide efflux among low-level resistant strains. From our laboratory collect...

Fire susceptibility modeling is crucial for sustaining and managing forests among many other valuable land resources. With 56% of its area covered by forests, Arkansas known as the “natural state”. About 1000 wildfires occurred burned more than 10,000 acres each year during 1981–2018. In this paper, we use remote-sensing-based machine learning methods to address natural anthropogenic factors in...

We studied adenosine triphosphate (ATP) synthesized by bacteria in tube dilution cultures to devise a rapid antibacterial susceptibility test. The ATP level was determined with a firefly (Photinus pyralis) luciferin/luciferase bioluminescence assay, which allows a direct quantifying of bacteria above 10,000 CFU/ml. At sub-MIC, total bacterial ATP levels were paralleled by increased viable bacte...

Cross-resistance between zidovudine, stavudine, and lamivudine was studied, using purified recombinant reverse transcriptase from a zidovudine-susceptible and -resistant pair of clinical isolates of human immunodeficiency virus type 1. The zidovudine-resistant isolate exhibited low-level cross-resistance to both stavudine and lamivudine in drug susceptibility assays. Enzyme from the resistant i...

Rats with polycythemia induced by exposures to simulated high altitudes developed a significantly higher incidence of endocarditis following intravenous bacterial injections than rats with cobalt polycythemia or ground level controls. No increase occurred in altitude rats when polycythemia was prevented by repeated bleedings. These findings suggest that both polycythemia and hypoxia are necessa...