Insulin-loaded microemulsions for transdermal delivery were developed using isopropyl myristate or oleic acid as the oil phase, Tween 80 as the surfactant, and isopropyl alcohol as the cosurfactant. The pseudoternary phase diagrams were constructed to determine the composition of microemulsions. The insulin permeation flux of microemulsions containing oleic acid as oil phase through excised mou...

Achieving a desirable percutaneous absorption of drug molecule is a major concern in formulating dermal and transdermal products. The use of penetration enhancers could provide a successful mean for this purpose. The aim of this study was to develop Clotrimazole gel and to evaluate the effect of almond oil and tween 80 (in different concentrations), on the permeation of drug through rabbit skin...

The cardiovascular effects of two concentrations of Tween 80 (polyoxyethylene sorbitan mono-oleate), a surface-active agent commonly used to prevent aggregation of radionuclide-labeled microspheres, were examined in conscious dogs. Two types of adverse reactions were noted. The first (Type A) consisted of reductions in cardiac dimensions as well as hypotension and tachycardia. The second (Type ...

Despite its potentially adverse effects on lung development and function, supplemental oxygen is often used to treat premature infants in respiratory distress. To understand how neonatal hyperoxia can permanently disrupt lung development, we previously reported increased lung compliance, greater alveolar simplification, and disrupted epithelial development in adult mice exposed to 100% inspired...

Background: Recently, concerns have been raised regarding the environmental and public health safety of azo dyes, most widely used synthetic dyes. The membrane technique has introduced as one efficient methods for dye removal treatments. Polyvinylidene fluoride (PVDF) manipulated by surfactants was studied dye, carmoisine. Methods: PVDF prepared via non-solvent-induced phase separation (NIPS) t...

Abstract The optimum processing conditions for PEDOT:PSS and PEDOT:PSS/Tween 80 cast films were investigated by considering film quality resistivity. thermal stabilities of these materials found to strongly influence the accessible annealing temperatures, especially in presence conductivity-enhancing agent Tween 80. resistivities with without decreased up 85% increases both temperature time unt...