Abstract We consider the problem of recovering three-dimensional atomic structure a flexible macromolecule from heterogeneous cryogenic electron microscopy (cryo-EM) dataset. The dataset contains noisy tomographic projections electrostatic potential macromolecule, taken different viewing directions, and in case, each cryo-EM image corresponds to conformation macromolecule. Under assumption that...

Isostructural Ln(III) mononuclear complexes [Ln(NO3)2L]PF6·MeCN (Ln = Nd, Tb, or Dy; L denotes a helical hexa-dentate ligand) were synthesized, and their slow magnetic relaxation behavior was investigated. In these complexes, oblate-type Ln(III) ions are located in an axially stressed ligand field with two nitrate anions, and can exhibit single-molecule magnet (SMM) behavior. Field-induced SMM ...

BACKGROUND It is well known that a low skeletal muscle mass (SMM) is associated with stroke. However, it is unknown whether increasing muscle mass can prevent stroke. METHODS This community-based cross-sectional study was supported by the regional government. SMM measurements and brain computed tomography was performed in 722 stroke-free and dementia-free subjects (aged 50-75 years). Subjects...

OBJECTIVE Cell therapy in the myocardium has been mainly performed with satisfactory results using 2 cell types: skeletal myoblasts (myogenic) and mesenchymal cells (angiogenic). This study assessed the combined transplantation of those 2 cell types (SMM) into infarcted rats. METHODS Myocardial infarction was induced by ligature of the left coronary artery in 26 Wistar rats. After one week, t...

Success of any software system largely looms upon its vigilance efficiency that prompts organizations to meet the set of objectives in the arena of networks. In the highly competitive world, everything appears to be vulnerable; information system is also not an exception to this fact. The security of information system has become a cause of great concern. On the contrary, till time the software...

Recent studies have indicated that the ratio of C-reactive protein to albumin (CRP-Alb ratio) is associated with clinical outcomes in patients with disease. We examined the predictive value of this ratio in patients undergoing hemodialysis (HD). In this cross-sectional study, 91 eligible adult HD patients were analyzed, and the correlation between the CRP-Alb ratio and skeletal muscle mass norm...

We present Expanded Very Large Array and Arecibo observations of two lensed submm galaxies at z ∼ 2.5, in order to search for redshifted 22.235 GHz water megamaser emission. Both SMM J14011+0252 and SMM J16359+6612 have multi-wavelength characteristics consistent with ongoing starburst activity, as well as CO line emission indicating the presence of warm molecular gas. Our observations do not r...

Smoldering multiple myeloma (SMM) is a plasma cell disorder first described in 1980 when 6 patients were observed to meet the diagnostic criteria of multiple myeloma, defined as bone marrow plasmacytosis of 10% or greater or M protein level of 3 g/dL or greater, but did not have end-organ damage. Subsequent studies showed that the cumulative risk of SMM progression to symptomatic myeloma in 15 ...

We have established a cell line from hypertrophied rabbit urinary bladder smooth muscle (SM) that stably expresses SM myosin (SMM). These cells, termed BSM, are spindle shaped and form swirls, similar to the "hills and valleys" described for cultured aortic SM cells. Western blotting revealed that BSM expresses the amino-terminal SMM heavy chain isoform SM-B, the carboxy-terminal SM1 and SM2 is...

Maintenance of the structural macromolecule peptidoglycan (PG), which involves regulated cycles of PG synthesis and PG degradation, is pivotal for cellular integrity and survival. PG fragments generated from the degradation process are usually efficiently recycled by Gram-negative bacteria. However, Neisseria gonorrhoeae and a limited number of Gram-negative bacteria release PG fragments in amo...