Yüzyılı aşkın geçmişi olan kök hücreler, günümüzde birçok hastalığın tedavisi için araştırma konusu olmaya devam etmektedir. Rejeneratif tıbbın da ilgi odağı hücreler; uzun süre bölünebilme, kendini yenileme ve farklılaşma özelliklerine sahiptir. Kök hücrelerde simetrik asimetrik hücre bölünmesi olmak üzere iki farklı bölünme şekli görülmektedir. hücreler telomerlerini tamamlayabildiği normal h...

considering the emerging importance of phenotypic markers as indicators of cell function and differentiation, we studied patterns ofcd44 and cd45rb expression in cd8+ murine t cells with prior exposure to antigen or staphylococcal enterotoxin b ( seb ). following in vivo priming with two purified protein derivatives (one from a virulent who strain and the other from an avirulent strain), t cell...

Tumor-derived exosomes possess significant clinical relevance due to their unique composition of genetic and protein material that is representative of the parent tumor. Specific isolation as well as identification of proportions of these clinically relevant exosomes (CREs) from biological samples could help to better understand their clinical significance as cancer biomarkers. Herein, we prese...

Gold nanorod molecular probes (GNrMPs) were designed and fabricated for multiplex identification of cell surface markers in HBECs. Cells were probed directly using dark field microscopy integrated with a spectral imager for simultaneous detection of up to three surface markers. The immunophenotype composition of these cell lines indicative of their metastasis potential was assessed using the GN...

in our study of surface markers of iranian children affected by acute lymphocytic leukemia, the majority(80 %)had non-t, non-b, or null cell leukemia. the null- cell l e ukemia had a better p r ogno s l s as was conf irmed by o t h ers. twe l v e of our patie nts who had null cell l e ukem i a are a live and well 18 mont hs to 20 mont hs a f t e r initiat i on of the r a py. three of t he patie...

Surface Plasmon Resonance (SPR) is an established technique for detection of molecular binding. More recently, new experimental set ups transformed SPR in a label-free and real-time detector of specific cell binding to an immobilized ligand. In this work, Surface Plasmon Resonance Imaging (SPRi) was employed to investigate the feasibility of a multiplex sensor to detect simultaneously 44 differ...