Horseradish peroxidase (HRP), has gained significant interests in biotechnology, especially in biosensor field and diagnostic test kits. Hence, its solvent-exposed lysine residues 174, 232, and 241 have been frequently modified with the aim of improving its stability and catalytic efficiency. In this computational study, we investigated the effects of Lys-to-Glu substitutions on HRP structure t...

Dissipation of charges built up near the surface of insulators due to space environment interaction is central to understanding spacecraft charging. Conductivity of insulating materials is key to determine how accumulated charge will distribute across the spacecraft and how rapidly charge imbalance will dissipate. To understand these processes requires knowledge of how charge is deposited withi...

Screening of a strongly charged macroion by multivalent counterions is considered. It is shown that counterions form a strongly correlated liquid at the surface of the macroion. Cohesive energy of this liquid leads to additional attraction of counterions to the surface, which is absent in conventional solutions of the Poisson-Boltzmann equation. Away from the surface this attraction can be take...

surface of mesostructured silica, kit-6, was modified by grafting 3-aminopropyl-triethoxysilane (aptes) to have the positive charge, and thus, to provide sites for the immobilization of h3pw12o40 (pw12).  this modified-nanosized mesoporous silica (pw12-aptes@ kit-6) was characterized by ftir, xrd, bet and tem. the oxidation of sulfides occurs effectively and selectively with h2o2 as the oxidant...

Acid-base titration experiments and electrostatic force microscopy (EFM) were used to investigate the cell surface electrochemical heterogeneity of the Fe(III)-reducing bacteria, Shewanella putrefaciens. The acid-base titrations extended from pH 4 to 10, and the titration data were fit using a linear programming pKa spectrum approach. Overall, a five-site model accounted for the observed titrat...

Many theoretical studies were devoted in the past to ion-specific effects trying to interpret a large body of experimental evidence, such as surface tension at air/water interfaces and force measurements between charged objects. Although several mechanisms were suggested to explain the results, such as dispersion forces and specific surface-ion interactions, we would like to suggest another sou...

We show that minimal SO(10) Grand Unification models where the fermions have Yukawa couplings to only one (complex) 10 and one 126 of Higgs scalars lead to a very predictive neutrino spectrum. This comes about since the standard model doublet contained in the 126 of Higgs (needed for the see–saw mechanism) receives an induced vacuum expectation value at tree–level, which, in addition to correct...

Neutrino oscillations give clear evidence for non-vanishing neutrino masses and lepton-flavor violation (LFV) in the neutrino sector. This provides strong motivation to search for signals of LFV also in the charged lepton sector, and to probe the SUSY seesaw mechanism. We compare the sensitivity of rare radiative decays on the right-handed Majorana mass scale MR with the reach in slepton-pair p...

We have studied the bulk and interfacial properties of a dipolar-quadrupolar fluid based on an extended modified mean-field density-functional theory. Effects of a uniform electric field on the bulk and interfacial properties are also studied. Results of the coexisting vapor-liquid densities, interfacial profiles of the density and orientation order parameters, the surface tension, and their de...

where ky > 0 and kz > 0. Show that for small ripples (a d), this leads to a reflected wave as if a = 0, plus two surface waves that are attenuated exponentially with z. What is the relation between the grating wavelength d and the optical wavelength λ such that the x component of the phase velocity of the surface waves is the speed of light, c? In this case, a charged particle moving with vx ≈ ...