OBJECTIVE To examine the pathophysiological significance of adrenomedullin in the pulmonary circulation by investigating the relation between plasma concentrations of adrenomedullin and central haemodynamics in patients with mitral stenosis. METHODS Plasma concentrations of adrenomedullin in blood samples obtained from the femoral vein, pulmonary artery, left atrium, and aorta were measured b...

The abnormalities of pulmonary arterial blood supply in mitral stenosis, consisting primarily of constriction of lower lobe vessels with resultant upper lobe preferential flow, was assessed by means of pulmonary angiography in 30 patients with mitral stenosis uncomplicated by other cardiac diseases. The abnormalities in blood flow correlated best with both the pulmonay artery pressure and the p...

Extrinsic compression of the pulmonary arteries by mediastinal masses, while rare, is the most common cause of non-congenital peripheral pulmonary artery stenosis. Granulocytic myeloid sarcomas are an extramedullary manifestation of acute myeloid leukemia, with a wide variability in their presentation. They can present either de novo as soft tissue masses or in conjunction with acute myeloid le...

Pulmonary vein stenosis is recognised as a rare, silent cause of pulmonary hypertension. ' The condition can occur with or without intracardiac anomalies. '3 The presence of lesions, such as ventricular septal defect, which cause pulmonary hypertension in their own right, can make suspicion of associated pulmonary venous obstruction difficult. In only one of the four reported cases4-7 of ventri...

The width of the jet flow in the pulmonary artery was measured using a multigate pulsed Doppler system in a baby with severe pulmonary valve stenosis. The degree of stenosis estimated before operation agreed with the result obtained during surgery.

We report a rare case of isolated subpulmonary membrane leading to critical pulmonary stenosis in an infant. This anomaly needs to be differentiated from valvar pulmonary stenosis as both anomalies require different modality of treatment (surgical/catheter).

Tetralogy of Fallot is characterised by tetrad pulmonary stenosis, ventricular septal defect, overriding aorta and right hypertrophy. This case report addresses an array craniofacial anomalies associated with operated Fallot.

Acquired pulmonary stenosis was diagnosed in a 53 year old woman presenting with the unusual feature of an oral murmur. Mediastinotomy showed extensive malignant tissue surrounding the pulmonary artery, although a mediastinal mass was not evident on chest radiographs. Histological examination confirmed a pleomorphic adenocarcinoma, which has not previously been reported as causing acquired pulm...