Background: Inactivation of p53 and reactivation of telomerase expression are two of the most common events in human cancer. Results: Here we report the mechanisms used by p53, p63, and p73 to suppress telomerase expression. Conclusion: p53, p63, and p73 suppress telomerase expression through distinct pathways that involve E2F, E-box, c-Myc, and NF-YB. Significance: This study provides new insi...
