background: the inappropriate use of aminoglycosides has harmful effects such as the development of resistant pathogens and the incidence of nephrotoxicity and ototoxicity. therefore, drug utilization evaluation of these drugs may improve their usage remarkably. the aim of this study was to assess the usage pattern of amikacin in an internal medicine ward. methods: this cross-sectional study wa...

nowadays medical journals around the world have proven their vital role in communities’ health. nevertheless, one important question is always arising regarding these journals that are whether they should publish any advertisements? the aimed of the present review article was to discuss different issues raised whenever one would like to answer this question. in 2013, the pub med search engine w...

background due to its progressive nature in all aspects of life, addiction endangers the health of individuals, families and the society. objectives the purpose of this study was to determine the role of self-regulation and affective control in predicting interpersonal reactivity of drug addicts. materials and methods this research is a correlation study. the statistical population of this stud...

background: antibiotics can be life saving if they are used correctly, and can have unwanted side effects specially resistance with incorrect use. unfortunately in fear of no response, physicians use broad spectrum antibiotics meticulously. in this drug utilization evaluation (due), improper use of vancomycin and five broad-spectrum antibiotics are studied to find faults and solution for this p...

antibacterial drugs used in animal might result in deposition of residues in meat, milk and eggs. the presence of antimicrobial residues in animal-originated food is critical problem in many countries over the years. because, drug residues might result in various health hazards, both actual incidence of reactions and potential hazards perceived by the public, the most countries assess residue o...

indole is a nitrogen-containing heterocycle. it is a very important motif in agriculture and pharmacy. many compounds containing indole moiety has been isolated form nature. it is also an important part in natural alkaloids. tryptophan is an amino acid which posses indole. 3-sustituted indoles are the main group of its derivatives. because the wide-spread application of 3-substituted indolic co...

conclusions it was the first report on the blactx-m-15 gene emergence in clinical enterobacter spp. in iran. the current study demonstrated the predominant presence of the gene encoding ctx-m-15 among esbl producing enterobacter spp. commonly with a large plasmid, in the setting. background enterobacter spp. is increasingly recognized as an important nosocomial pathogen and implicated in many e...

to study the resistance to standard dosage of clopidogrel among iranian patients following percutaneous coronary intervention measured by platelet aggregation test.patients undergoing percutaneous coronary intervention in imam hussein medical center, tehran, iran, who were under treatment with aspirin, but had no history of clopidogrel usage, entered the study. patients received standard dosage...

in this work we synthesized nano hydroxyapatite (hap)  by sol-gel method, then we functionalized hydroxyapatite nanoparticle by use of  3-aminopropyl trimethoxysilane (aptms) , to improve the loading and control release of sulfasalazine drug bonded to aptms. the drug release patterns from sulfasalazine loaded hap nanoparticles at ph value 8 for 6h, sulfasalazine loaded functionalized hap nanopa...

emerging new medications in the treatment of hbv produces hope and promises for curing of hbv. over the past decade, the development of oral nucleoside/nucleotide analogs (nas) with favorable potencies and tolerabilities has led to substantial advances in chronic hepatitis b (chb) therapy. the oral anti-hbv agents currently approved are lamivudine, adefovir dipivoxil , entecavir , telbivudine, ...