BACKGROUND Subclinical hypothyroidism has been associated with depressive symptoms in cross-sectional studies, but prospective data and data on subclinical hyperthyroidism are scarce. METHODS In the Leiden substudy of the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER), thyroid-stimulating hormone and free T4 levels were measured at baseline and repeated after 6 months in ad...

BACKGROUND Thyroid disorders are associated with pregnancy complications. Universal screening is currently not recommended because of a lack of evidence on the effectiveness of treatment. Women with hyperthyroidism and hypothyroidism evidently require treatment but this is less clear for women with subclinical hypothyroidism and thyroid autoimmunity. Therefore, we conducted a systematic review ...

Introduction: Hashimoto’s thyroiditis is a chronic autoimmune lymphocytic characterised by thyroid autoantibodies. Early detection and treatment of this condition help in reducing the morbidity mortality associated with it. The aim study was to find out prevalence among patients disorders visiting tertiary care centre. Methods: A descriptive cross-sectional conducted outpatient department Data ...

Dear Editor, There is substantial degree of disagreement regarding the mechanisms of possible association between thyroid dysfunction and Alzheimer’s disease. For example, it is not settled which indicator of thyroid function is the best marker of this relationship. Since thyroid disorders could be considered as treatable risk factors for Alzheimer’s disease, identification of any relationship ...

Background:Thyroid diseases and diabetes mellitus are the two most common endocrine disorders encountered in clinical practice. Type 2 (T2DM) has an intersecting underlying pathology with thyroid dysfunction. Insulin hormones intimately involved cellular metabolism thus excess or deficit of either these result functional derangement other.Despite absence definite guidelines regarding screening ...

INTRODUCTION Neuropsychological changes are still controversial in patients with subclinical hypothyroidism (SH). The objective of this study is to assess these changes. METHOD Cross-sectional study comparing the results of the neurocognitive evaluation of 65 SH patients and 31 individuals without thyroid disease. Subclinical hypothyroidism was defined as at least two elevated serum TSH level...

Background It is well documented that overt hypothyroidism is associated with adverse pregnancy outcomes, but studies of subclinical hypothyroidism have demonstrated conflicting results. Objective Thyroid hormones are known to regulate mitochondrial function, and the aim of this study was to examine the possible relationship of subclinical hypothyroidism and mitochondrial dysfunction to adver...

Background: Numerous hormonal changes and metabolic demands occur during pregnancy, resulting in complex maternal thyroid function. Thyroid disorder is the second most common endocrine found pregnancy next to diabetes group. It affects 1–2% of women reproductive age. Overt hypothyroidism complicates 0.3–0.5% pregnancies. The incidence subclinical pregnant about 2–3%. Hyperthyroidism present 0.1...

BACKGROUND AND PURPOSE Subclinical hyperthyroidism is associated with adverse cardiovascular events, including stroke and atrial fibrillation. However, its impact on functional outcome after stroke remains unexplored. METHODS A total of 165 consecutively recruited patients admitted for ischemic stroke were included in this observational prospective study. Blood samples were taken in the morni...

Progressive disease that is Diabetes a chronic disorder characterized by elevated blood glucose levels. The global prevalence of this has nearly doubled among adults. Mellitus (DM) and thyroid diseases are the most common endocrine disorders in clinical practice. Several studies have shown diabetes mellitus associated with an increased incidence disorders. main aim study was to assess patients ...