Vertebrate gap junctions, composed of proteins from the connexin gene family, play critical roles in embryonic development, co-ordinated contraction of excitable cells, tissue homoeostasis, normal cell growth and differentiation. Phosphorylation of connexin43, the most abundant and ubiquitously expressed connexin, has been implicated in the regulation of gap junctional communication at several ...

The paper suggests a way of modeling belief changes within the tradition of formal belief revision theories. The present model extends the scope of traditional proposals, such as AGM, so as to take care of “structural belief changes” – a type of radical shifts that is best illustrated with, but not limited to, instances of scientific discovery; we obtain AGM expansions and contractions as limit...

The freeze-fracture appearance of rat stomach and liver gap junctions changes after uncoupling procedures such as inhibition of the metabolism of perfusion with hypertonic sucrose. In control stomach, either fixed immediately or kept for 1 h in a well-oxygenated Tyrode's solution at 37 degrees C, most gap junctions between mucous cells contain particles irregularly packed at an average center-t...

Schizophrenia is a chronic progressive disorder that has at its origin structural brain changes in both white and gray matter. It is likely that these changes begin prior to the onset of clinical symptoms in cortical regions, particularly those concerned with language processing. Later, they can be detected by progressive ventricular enlargement. Current magnetic resonance imaging (MRI) technol...

We describe Tree Flow, a new technique for visualizing changes to the structure of a hierarchy, and discuss a prototype tool that implements this method. Roughly speaking, Tree Flow works by creating a timeline in which the x-axis corresponds to date information, and the y-axis corresponds to the depth-first ordering of data in a time-varying tree structure. We present several examples of real-...

This paper analyzes the structural change and performance of the Nepalese economy over the period of 1965 to 2009, specially focusing on the impact of IMF and World Bank's structural adjustment program implemented since the mid-1980s based on the Washington consensus. The performance of Nepalese economy has not improved much after the implementation of a series of structural adjustment programs...

Luminescence data have often been used to study imperfections and to characterize lattice distortions because the signals are sensitive to changes of structure and composition. Previous studies have included intentionally added probe ions such as rare earth ions to sense distortions in local crystal fields caused by modified structural environments. An under-exploited extension of this approach...

Introduction Analyzing the evolution of agricultural research and development policy in South Africa is a fascinating but difficult task, primarily because of the large number of structural, institutional, and political changes that took place during the 20th century. This chapter tracks the history of South Africa's agricultural research and development system against this background, highligh...

It has been observed that certain char particles shrink when oxidized under kinetically limited conditions, instead of reacting at constant diameter, as expected. This study was perfonned to determine whether or not char from PSOC 1451 coal, prepared at different temperatures would also shrink during low temperature gasification. Coal chars, formed at l 200K and 1600K, were levitated in the ele...