Introduction Anabolic-androgenic steroids (AAS) are synthetic derivatives of which frequently utilized in order to increase muscle mass and strength. Estimates AAS abuse vary according different studies. However, a global lifetime prevalence 3.3% has been reported. The increasing illicit use over the years raised serious public health concerns. Objectives To report clinical case review psychopa...

BACKGROUND Epidural steroid injection is a low-risk alternative to surgical intervention in the treatment of lumbar disc herniation. The objective of this study was to determine the efficacy of epidural steroid injection in the treatment of patients with a large, symptomatic lumbar herniated nucleus pulposus who are surgical candidates. METHODS One hundred and sixty-nine patients with a large...

BACKGROUND Patients' understanding of their condition affect the choice of treatment. The aim of this study is to evaluate patients' understanding and treatment preferences before and after an information session on the treatment of acute optic neuritis. METHODS Participants were asked to complete a questionnaire consisting of 14 questions before and after an information session presented by ...

Lichen planus is a relatively common mucocutaneous lesion in adults but it rarely seen paediatric patients. Here we presenting case of oral lichen 10 years old boy. The diagnosis was made on the basis clinical features only. Topical steroid therapy most given planus. This wastreated with novel treatment modality topical tacrolimus 0.03% and patient responded well to treatment.

Nephrotic syndrome is the most common glomerular disorder in children, and corticosteroids are the first choice of treatment. While the majority of children respond to corticosteroid therapy, a few do not enter remission after daily therapy for 1-2 months, hence showing steroid-resistance. Most of these children show focal and segmental glomerulosclerosis (FSGS) upon renal biopsy. Steroid resis...

OBJECTIVE To learn if oral steroid treatment can alter the signs of primary progressive aphasia (PPA). Many patients with PPA have had a vasectomy and there is a possible link between vasectomy and autoimmune diseases. If PPA is, at least in part, an autoimmune disease, patients might improve with immunosuppressant treatment. DESIGN Case report. SETTING Cognitive and memory clinic. PATIEN...

BACKGROUND Treatment of severe asthma may include high dose systemic-steroid therapy which is associated with substantial additional morbidity. This study estimates the additional healthcare costs associated with steroid-induced morbidity by comparing three patients groups: those with severe asthma, moderate asthma and no asthma. METHODS Patients with severe asthma (n = 808, GINA step 5 treat...

Background. High recurrence rates of nephrotic syndrome in children and consequences the form steroid dependence a high risk side effects from corticosteroids as result involve immunosuppressive steroid-preserving agents that would increase long-term remission. Rituximab, chimeric anti-CD20 monoclonal antibody inhibits CD20-mediated B-cell proliferation differentiation, has been identified poss...

PURPOSE The purpose of this study was to describe a combination treatment for choroidal neovascular (CNV) membrane, secondary to punctate inner choroidopathy (PIC). PATIENT AND METHODS A 44-year-old female patient was diagnosed with PIC complicated by the development of recurrent juxtafoveal neovascular membrane. The treatment included a sequence of monotherapy regimens: systemic steroid ther...