نتایج جستجو برای: steroid resistant nephrotic syndrome

تعداد نتایج: 842591  

2010
Atsushi Komatsuda Hideki Wakui Hiroshi Ohtani Takashi Nimura Ken-ichi Sawada

A 78-year-old woman developed acute-onset nephrotic syndrome. A renal biopsy showed mild mesangial proliferative glomerulonephritis. Immunofluorescence studies revealed granular IgG3- λ deposits within the mesangial area and along the glomerular capillary walls. Electron microscopy showed mesangial and subendothelial granular electron-dense deposits. The pattern of deposition was predominantly ...

2015
Norishige Yoshikawa Koichi Nakanishi Mayumi Sako Mari S Oba Rintaro Mori Erika Ota Kenji Ishikura Hiroshi Hataya Masataka Honda Shuichi Ito Yuko Shima Hiroshi Kaito Kandai Nozu Hidefumi Nakamura Takashi Igarashi Yasuo Ohashi Kazumoto Iijima

In this multicenter, open-label, randomized controlled trial, we determined whether 2-month prednisolone therapy for steroid-sensitive nephrotic syndrome was inferior or not to 6-month therapy despite significantly less steroid exposure. The primary end point was time from start of initial treatment to start of frequently relapsing nephrotic syndrome. The pre-specified non-inferiority margin wa...

Journal: :Indian pediatrics 2008
Arvind Bagga Uma Ali Sushmita Banerjee Madhuri Kanitkar Kishore D Phadke Prabha Senguttuvan Sidharth Sethi Mehul Shah

JUSTIFICATION In 2001, the Indian Pediatric Nephrology Group formulated guidelines for management of patients with steroid sensitive nephrotic syndrome. In view of emerging scientific evidence, it was felt necessary to review the existing recommendations. PROCESS Following a preliminary meeting in March 2007, a draft statement was prepared and circulated among pediatric nephrologists in the c...

Journal: :British medical journal 1969
M W Moncrieff R H White C S Oggs J S Cameron

Forty-six children with the nephrotic syndrome whose renal biopsy specimens showed minimal changes and whose response to corticosteroid therapy was unsatisfactory were treated with cyclophosphamide. Three patients were completely steroid-resistant from the outset and the remainder were steroid-dependent. In several patients steroids controlled the condition less effectively with time. Most pati...

2017
Tomohiro Nakata Ryo Ishida Yuu Mihara Atsuko Fujii Yoshimoto Inoue Tetsuro Kusaba Tsuyoshi Isojima Yutaka Harita Chiaki Kanda Sachiko Kitanaka Keiichi Tamagaki

BACKGROUND Nail-patella syndrome (NPS) is an autosomal dominant disorder caused by mutations in the LMX1B gene and is characterized by nail dysplasia, skeletal abnormalities, and nephropathy. We herein report a case of steroid-resistant nephrotic syndrome (SRNS) prior to overt orthopedic symptoms in a patient with NPS. CASE PRESENTATION A 24-year-old woman presented to our hospital with knee ...

2015
Julien Hogan Marc Fila Véronique Baudouin Michel Peuchmaur Georges Deschênes Olivier Niel

BACKGROUND Nephrotic syndrome is a relatively rare but serious condition in children. Infantile nephrotic syndrome often has a genetic origin; the treatment is then symptomatic, with a poor prognosis, and a rapid evolution to chronic kidney disease. However, non-genetic infantile nephrotic syndrome has been identified. Here we report for the first time in a child a nephrotic syndrome as the sol...

Journal: :Saudi medical journal 2006
Jameela A Kari Abdulmohsen Alkushi Hammad O Alshaya

C (CHL) had been used as treatment for childhood nephrotic syndrome (NS) for more than half a century.1 It was used mainly in children with steroid sensitive nephrotic syndrome (SSNS) as steroid sparing agent in those with frequent relapsing or steroid dependent course.2 However, it was observed to result in higher rates of severe side effects and recommended as a second line drug after cycloph...

Journal: :Journal of Gandhara medical and dental sciences 2023

ABSTRACT A 13-year-old boy known for steroid-resistant nephrotic syndrome taking cyclosporine the last four years was referred from one private hospital non-response to treatment and decreased hearing. On detailed history, it revealed that hearing loss started after initiation of with during first year, patient not properly followed issues. Rather continued despite no response treatment. The ra...

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