Trimethoprim/sulfamethoxazole (TMP/SMX) resistance remains a serious threat in the treatment of Stenotrophomonas maltophilia infections. We analyzed an international collection of 55 S. maltophilia TMP/SMX-sensitive (S) (n=30) and -resistant (R) (n=25) strains for integrons; sul1, sul2 and dhfr genes; and insertion element common region (ISCR) elements. sul1, as part of a class 1 integron, was ...

Clinical strains of Stenotrophomonas maltophilia are often highly resistant to multiple antibiotics, although the mechanisms of resistance are generally poorly understood. Multidrug resistant (MDR) strains were readily selected by plating a sensitive reference strain of the organism individually onto a variety of antibiotics, including tetracycline, chloramphenicol, ciprofloxacin, and norfloxac...

OBJECTIVE To describe clinical presentation, antibiotic susceptibility, and outcomes in patients with Stenotrophomonas maltophilia endogenous endophthalmitis. DESIGN Retrospective case series. PARTICIPANTS Four eyes of four patients with S. maltophilia endogenous endophthalmitis. METHODS Retrospective chart review of culture-positive S. maltophilia endogenous endophthalmitis treated at L ...

24 Stenotrophomonas maltophilia is an important global opportunistic pathogen for which 25 limited therapeutics are available because of the emergence of multidrug-resistant strains. 26 A novel bacteriocin, maltocin P28, which is produced by S. maltophilia strain P28, is the 27 first-identified phage tail-like bacteriocin from S. maltophilia. Maltocin P28 resembles a 28 contractile but non-flex...

Stenotrophomonas maltophilia is an important global opportunistic pathogen for which limited therapeutics are available because of the emergence of multidrug-resistant strains. A novel bacteriocin, maltocin P28, which is produced by S. maltophilia strain P28, may be the first identified phage tail-like bacteriocin from S. maltophilia. Maltocin P28 resembles a contractile but nonflexible phage t...