Staphylococcus aureus is an important pathogenic bacterium that causes various infectious diseases. Extracellular vesicles (EVs) released from S. aureus contain bacterial proteins, nucleic acids, and lipids. These EVs can induce immune responses leading to similar symptoms as during staphylococcal infection condition and have the potential as vaccination agent. Here, we show that active immuniz...

Staphylococcus aureus is a frequent cause of infections in both the community and hospital. Worldwide, the increasing resistance of this pathogen to various antibiotics complicates treatment of S aureus infections. Effective measures to prevent S aureus infections are therefore urgently needed. It has been shown that nasal carriers of S aureus have an increased risk of acquiring an infection wi...

OBJECTIVES To determine the frequency of Staphylococcus aureus colonization among patients with acne and to compare the susceptibility patterns between the patients who are using antibiotics and those who are not using antibiotics. DESIGN Survey (cross-sectional) study of patients treated for acne. SETTING Dermatology outpatient office practice PARTICIPANTS The study included 83 patients ...

Staphylococcus aureus (S. aureus) is an important human pathogen, which commonly causes the acquired infectious diseases in the hospital and community. Effective and simple antibiotic treatment against S. aureus-related disease becomes increasingly difficult. Developing a safe and effective vaccine against S. aureus has become one of the world's hot spots once again. The key issue of developing...

PURPOSE To study the prevalence of methicillin-resistant Staphylococcus aureus among S. aureus ocular infections in a tertiary health center in Brazil and compare antibiotic susceptibility patterns between MRSA and methicillin-susceptible S. aureus isolates. METHODS Electronic records from the ocular microbiology laboratory of the Universidade Federal de São Paulo were retrospectively reviewe...

BACKGROUND Recently, we found that Staphylococcus aureus produces extracellular vesicles (EV) that contain pathogenic proteins. Although S. aureus infection has been linked with atopic dermatitis (AD), the identities of the causative agents from S. aureus are controversial. We evaluated whether S. aureus-derived EV are causally related to the pathogenesis of AD. METHODS Extracellular vesicles...

Staphylococcus aureus is an opportunistic pathogen and variable component of the human microbiota. A characteristic of atopic eczema (AE) is colonization by S. aureus, with exacerbations associated with an increased bacterial burden of the organism. Despite this, the origins and genetic diversity of S. aureus colonizing individual patients during AE disease flares is poorly understood. To exami...

background and objective: vancomycin is frequently the antibiotic of choice for the treatment of infections caused by methicillin-resistant staphylococcus aureus (mrsa). for the last years, the incidence of vancomycin-intermediate s. aureus (visa) and vancomycin-resistant s. aureus (vrsa) has been increased in various parts of the world. the present study was carried out to determine the presen...

conclusions the present study reports on a high rate of multi-drug resistance, the predominance of the frequency of class 1 integron, and the emergence of spa type t790 among iranian staphylococcus aureus strains. the results revealed that the dissemination of multi-drug resistance among staphylococcus aureus isolates may be associated with the presence of integrons. therefore, continuous surve...

conclusion: the outcome of this study show that spa and coa typing are suitable meth­ods for mrsa isolates typing because it is easy to use and interpret them, and that these methods can be useful in infection source detection and its control especially in epidemic situations. result: pcr results showed seven different patterns for staff and five different patterns for patients based on spa gen...