Daytime sleepiness is a commonly reported adverse effect associated with psychotropic agents that may impair cognitive performance and functioning. The objective of this post-hoc analysis was to evaluate the long-term effects of lurasidone and quetiapine XR on daytime sleepiness and neurocognitive performance during a 6-month, double-blind continuation study, in subjects who completed an initia...

PURPOSE OF REVIEW Fragmented sleep, prolonged work hours, misalignment of sleep-wake cycles, and an expectation to make medical decisions when alertness levels are reduced are pervasive in neurology residency training. Sleep loss in residency training can lead to cognitive and psychosocial impairment and accidents, compromise patient care, and reduce the trainee's quality of life. Neurology res...

INTRODUCTION Sleep deprivation among training physicians is of growing concern; training physicians are susceptible due to their prolonged work hours and rotating work schedules. The aim of this study was to determine the prevalence of self-perceived sleepiness in emergency training physicians, and to establish a relationship between self-perceived sleepiness, and quality of life. METHODS Pro...

BACKGROUND Adverse effects of obstructive sleep apnea (OSA), including sleep deprivation, can contribute to the progression of heart failure. The usual indication to diagnose and treat sleep apnea is subjective sleepiness. Previous studies suggest that patients with both heart failure and obstructive sleep apnea often do not complain of sleepiness, albeit their sleep time may be reduced. Theref...

10.2217/14750708.2.2.191 © 2 part of Modafinil is an oral wake-promoting agent, initially approved in December 1998 for the treatment of excessive sleepiness associated with narcolepsy. Based on the results of additional randomized, placebo-controlled studies, the indication for modafinil was expanded in January 2004 to include excessive sleepiness associated with obstructive sleep apnea/hypopn...

Narcolepsy is an increasingly recognized sleep disorder characterized by excessive daytime sleepiness, symptoms of dissociated/abnormal rapid eye movement (REM) sleep, disrupted nocturnal sleep, and cataplexy. Although daytime sleepiness is the most disabling symptom, significantly disrupted sleep at night results in a similar total amount of sleep over 24 hours compared to controls. Many of th...

Yawning is related to sleep/wake transitions and time of day, probably reflecting the time course of sleepiness. As aging modifies sleep-wake and sleepiness rhythms, we suppose that yawning frequency and its time course vary as a function of age. Thirteen aged healthy subjects (77.15 +/- 4.09 years) and 12 young adults (24.41 +/- 3.31 years) were instructed to keep their habitual sleep schedule...

Sleepiness is a major risk factor for serious injury and death in accidents. Although it is important to develop countermeasures to sleepiness to reduce risks, it is equally important to determine the most effective timing for these countermeasures. To determine optimum timing for necessary countermeasures, we must be able to predict performance errors. This study examined the predictability of...

STUDY OBJECTIVES To examine the relationship of gender to subjective measures of sleepiness, including the Epworth Sleepiness Scale (ESS), in a community-based population. DESIGN A cross-sectional study. SETTING/PARTICIPANTS Multicenter Sleep Heart Health Study participants (N = 6.440, 52% women) recruited from ongoing cohort studies. INTERVENTIONS N/A. MEASUREMENTS Scores from the ESS,...