Understanding the composition of paleodiets is crucially important for the archaeological investigation of lifeways and subsistence practices within ancient societies. Among the numerous research methods capable of investigating various elements of paleodiets, the use of stable isotope analysis has become increasingly popular. Advantages of this research technique include its ability to recogni...

Picarro WS-CRDS-based analyzers are the first instruments to combine simple, turnkey operation with sensitivity and precision better than or equal to the IRMS (isotope ratio mass spectrometer) systems traditionally used in stable isotope labs. This opens the door for widespread exploitation of stable isotope studies in fields such as carbon/water cycle research, GHG (greenhouse gas) monitoring,...

Stable isotope ratios of carbon and nitrogen in bone have become increasingly frequent inclusions in archaeological reports over the past few decades. The majority of such studies has been done in North America, where the use of marine foods and the introduction of maize have been monitored. Similar questions have been addressed in Mesoamerica and South America. In Europe, stable isotope ratios...

The inherent sampling and preservational biases of the archaeological record make it difficult to quantify prehistoric human diets, especially in coastal settings, where populations had access to a wide range of marine and terrestrial food sources. In certain cases, geochemical proxies such as stable isotope ratios may be utilized to provide robust estimates on the relative proportions of vario...

An advantage of using LC-MS(WMS) for in vitro CYP inhibition screening is that it does not require extensive sample preparation and chromatographic separation. Attention must be paid, however, to ion suppression eŠects on analytes caused by the test compound as well as endogenous compounds. In this study, we have shown the ion suppression of 1?-hydroxymidazolam (analyte) and dextrorphan (IS) by...

The Hawaiian Islands offer a unique opportunity to test how changes in the properties of an isolated ecosystem are propagated through the organisms that occur within that ecosystem. The age-structured arrangement of volcanic-derived substrates follows a regular progression over space and, by inference, time. We test how well documented successional changes in soil chemistry and associated veget...

Unlike migratory seabirds with wide foraging ranges, resident seabirds forage in a relatively small range year-round and are thus particularly vulnerable to local shifts in prey availability. In order to manage their populations effectively, it is necessary to identify their key prey across and within years. Here, stomach content and stable isotope analyses were used to reconstruct the diet and...

The stable isotope ratios of carbon, oxygen, and hydrogen have been measured for a German oak in wood samples of roughly three years each, for the years 1712-1954 A.D., and correlated with the existing weather records from England, Basel, and Geneva to evaluate the empirical temperature coefficients. Isotope ratios in a second official oak, measured for the years 1530-1800 A.D., show the cold t...

Diode-laser absorption spectroscopy finds increasing applications in the emerging field of stable isotope research. To meet the requirements of the water isotopes measurement challenge in environmental research, ways have to be found to cope with the present limitations of spectroscopic systems. In this article, we discuss an approach based on the Stark effect in molecular spectra to reduce the...