In 110 patients with either stable or unstable angina, the morphology of coronary artery lesions was qualitatively assessed at angiography. Each obstruction reducing the luminal diameter of the vessel by 50% or greater was categorized into one of the following morphologic groups: concentric (symmetric narrowing); type I eccentric (asymmetric narrowing with smooth borders and a broad neck); type...

The clinical presentation of ischaemic heart disease includes stable and unstable angina pectoris, silent ischaemia, myocardial infarction, heart failure and sudden death [1]. For many years, unstable angina has been considered an intermediate syndrome between chronic stable angina and acute myocardial infarction. In recent years, its pathophysiology has been clarified and acute coronary syndro...

Management of cardiac symptoms in myasthenia gravis (MG) patients can be challenging. The aim of this report is to describe the safe use of ivabradine for stable angina in MG patients. A 48 y.o. woman, with MG diagnosis, presented stable angina. Therapies choices were reduced considering concomitant disease as well as previous and unsuccessful cardiologic managements. Ivabradine showed unexpect...

Ischemic heart disease is the world’s leading cause of mortality and also causes widespread morbidity and limitation of life-style. Coronary artery disease (CAD) is the predominant cause of ischemic heart disease and generally results from fixed coronary artery obstruction that limits myocardial oxygen delivery relative to demand. Mortality associated with CAD is relatively high and was estimat...

The clinical and pathological data from 46 patients who died during or shortly after coronary bypass surgery and one patient who died shortly after angiography were studied. Each patient was placed into one of three clinical categories of angina pectoris. Twelve were classified as having unstable angina pectoris, 20 as stable severe angina, and 15 as stable moderate angina. No significant diffe...

Background: Myocardial ischemia with its clinical symptom angina pectoris is associated with increased morbidity and mortality. Obstructive coronary artery disease (CAD) is not the only cause for cardiac ischemia and the prevalence of obstructive CAD in patients with stable angina pectoris is still discussed. Therefore, we investigated the prevalence of CAD in patients with stable angina pector...

BACKGROUND Genetic polymorphisms may affect the balance between coagulation and fibrinolysis and thereby affect individual vulnerability to acute myocardial infarction (MI) among patients with underlying coronary atherosclerosis. METHODS We enrolled 1375 patients with an initial clinical presentation of coronary disease. We genotyped 49 single nucleotide polymorphisms (SNPs) in 9 coagulation ...