PURPOSE In the present report we describe our clinical experience using specific image-based decision making and anatomic considerations for transcatheter valve-in-valve (ViV) implantation in degenerated xenografts with their pericardial leaflets externally mounted around the stent (Mitroflow [SORIN Group, Milan, Italy] or Trifecta [St. Jude Medical, St Paul, MN]). This design seems to increase...

BACKGROUND Mitral valve replacement in the presence of severe annular calcification is a technical challenge. CASE REPORT A 47-year-old lady who had undergone mitral and aortic valve replacement for rheumatic disease 27 years before presented with dyspnea. At reoperation, extensive mitral annular calcification was hindering the disc motion of the Starr-Edwards mitral prosthesis. The old prost...

From the Department of Oncology and International Outreach Program, St. Jude Children’s Research Hospital (S.C.H., C.-H.P.), and the Department of Pediatrics, University of Tennessee Health Sciences Center, College of Medicine (S.C.H., D.P.J., C.-H.P.) — both in Memphis. Address reprint requests to Dr. Howard at St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Barry-Longinotti Bld...

There are errors in the author affiliations. The publisher apologizes for the error. The affiliations should appear as shown here: Vikki G. Nolan, Kerri A. Nottage, Elliott W. Cole, Jane S. Hankins, James G. Gurney 1 Division of Epidemiology, Biostatistics and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA, 2 Department of Hematology, St. Jude Children’s ...

A 27-year-old man with a congenital heart disease consisting of a double inlet left ventricle s/p a classic Fontan palliation and oversewing of a regurgitant tricuspid valve in 1991 with enlargement of a bulboventricular foramen in 1997, transposition of the great arteries, subaortic stenosis, a left persistent superior vena cava (LSVC), and a hypoplastic mitral valve was followed up in an adul...

Affiliation: 1. St. Jude Children’s Research Hospital, Department of Genetics. 262 Danny Thomas Place, Memphis, TN 38105 USA Email addresses: [email protected] [email protected] [email protected] [email protected] 2. St. Jude Children’s Research Hospital, Department of Chemical Biology & Therapeutics. 262 Danny Thomas Place, Memphis, TN 38105 USA Email ...

Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN, (A.S.C., R.K.T., K.Y., E.G.S.), Department of Computational Biology, St Jude Children’s Research Hospital, Memphis, TN (Y.F.), Department of Integrative Biology and Physiology, University of California, Los Angeles, CA (X.Y.), Department of Laboratory Medicine, Division of Pathology, Karolinska Instituet, ...

Objective: The experience with the Carbomedics (CM) and the St. Jude Medical (SJM) bilea ̄et mechanical prostheses was evaluated to determine thromboembolic and hemorrhagic complications and predictive risk factors. Methods: From 1989 to 1994, a total of 625 patients had mitral valve replacement (CM, 240; SJM, 385); 32.5% (203), concomitant procedures and 32.8% (205), previous cardiac surgery, p...

The high incidence of thromboembolic complications of mechanical heart valves (MHV), primarily due to platelet activation by contact with foreign surfaces and by non-physiological flow patterns past the valve, still limits their success as permanent implants. The latter include elevated shear and turbulent stresses and shed vortices formed in the wake of the valve's leaflets during the decelera...