OBJECTIVE To measure sex-role beliefs of psychiatry residents and to examine bias in clinical appraisal. METHOD Residents (45 female, 51 male) evaluated 1 of 4 possible clinical case histories-a female or male patient with histrionic personality disorder (HPD) or antisocial personality disorder (APD)-and completed the Sex-Role Egalitarianism Scale (SRES). RESULTS As predicted, female reside...

Induction of the primary response gene egr-1 occurs rapidly following antigen receptor cross-linking in B lymphocytes. Antisense studies have demonstrated that this induction is necessary for their subsequent activation to this signal. The present study examines the molecular mechanism whereby the receptor-generated signals interact with the egr-1 promoter to elicit transcription. Deletion mapp...

The crop model CERES-Wheat in combination with the stochastic weather generator were used to quantify the effect of uncertainties in selected climate change scenarios on the yields of winter wheat, which is the most important European cereal crop. Seven experimental sites with the high quality experimental data were selected in order to evaluate the crop model and to carry out the climate chang...

Scenarios are alternative images of future and are useful tools for learning about complex environmental systems behaviour. The objective of this study is to generate future socio-economic cum emissions scenarios and projections for carbon emissions in each scenario for the time period up to 2030. There are not many studies available in India on scenario construction though different government...

Technology for sixth-generation (6G) mobile communication system is now being widely studied. A sub-Terahertz band expected to play a great role in 6G enable extremely high data-rate transmission. This paper has two goals. (1) Introduction of concept and propagation characteristics sub-Terahertz-band radio waves. (2) Performance evaluation intelligent reflecting surfaces (IRSs) based on beamfor...

Thrombin signaling in endothelial cells provides an important link between coagulation and inflammation. We report here that thrombin induces endogenous Egr-1 mRNA and Egr-1 promoter activity in primary human endothelial cells by approximately 6-fold and 3-fold, respectively. In transient transfection assays, deletion of the 3 cluster of serum response elements (SREs), but not the 5 cluster of ...

Objectives: Bone metastases (BM) and skeletal-related events (SREs) are frequent complications in patients with lung cancer. Whereas in non-small-cell lung cancer (NSCLC) incidence, prognostic impact, and risk factors are well established, there is only little knowledge in patients with small cell lung cancer (SCLC). We retrospectively evaluated the incidence of BM, SRE and their treatment in a...

Thrombin signaling in endothelial cells provides an important link between coagulation and inflammation. We report here that thrombin induces endogenous Egr-1 mRNA and Egr-1 promoter activity in primary human endothelial cells by approximately 6-fold and 3-fold, respectively. In transient transfection assays, deletion of the 3' cluster of serum response elements (SREs), but not the 5' cluster o...

Skeletal-related events (SREs) including pain, fractures, and hypercalcemia are a major source of morbidity for cancer patients with bone metastases. The receptor activator of NF-κB ligand (RANKL) is a key mediator of osteoclast formation and activity in normal bone physiology as well as cancer-induced bone resorption. The first commercially available drug that specifically targets and inhibits...

BACKGROUND Bone metastases are common in patients with hormone-refractory prostate cancer. In a study of autopsies of patients with prostate cancer, 65%-75% had bone metastases. Bone metastases place a substantial economic burden on payers with estimated total annual costs of $1.9 billion in the United States. Skeletal-related events (SREs), including pathologic fractures, spinal cord compressi...