In the title compound, C(6)H(6)O(4), inter- and intra-molecular hydrogen bonds are observed which help to establish the crystal structure. There are weak π-π interactions between pyran rings separated by 3.5692 (9) Å.

Present communication deals with the synthesis and characterization of various spiro thiazolinone heterocyclic compounds. 4-(4-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-ylsulfonyl)phenyl)-1-thia-4-azaspiro[4.5]decan-3-one (5) was synthesized by facile and fast heterocyclization reaction, which further underwent condensation with 4-chlorobenzaldehyde to afford 2-(4-chlorobenzylidene)-4-(4-(6,7-dihy...

The reactivity of quinoneimines towards ketene and diphenylketene was examined. N-Phenylbenzoquinoneirnines (I), (2) and also N-phenylnaphthoquinoneimine react with ketene to give the spiro-adducts (5), (7) and (1 1) respectively. These adducts were stable even after prolonged heating in high boiling solvent. Reaction of the above imines with diphenylketene also afforded 13- lactam spiro-a...

The aim of the work was to study antioxidant activity 4-R-3- (morpholinomethyl)-4H-1,2,4-triazole-5-thioles and their alkyl derivatives in vitro using method non-enzymatic initiation lipid peroxidation. Among 45 compounds studied, 8 showed varying degrees AOA. most pronounced AOA has 4-amino-3-(morpholinomethyl)-4H-1,2,4-triazole-5-thiol. It found that cases introduction alkyl-derivatives 4-R-3...

The privileged spiro[pyrrolidin-3,3'-oxindole] derivatives exhibit important biological activities. An enantioselective organocatalytic approach to the rapid synthesis of spiro[pyrrolidin-3,3'-oxindole] derivatives with high enantiopurity and structural diversity is described. The asymmetric catalytic three-component 1,3-dipolar cycloaddition of a broad range of methyleneindolinones with aldehy...

The biological properties of spiro-piperidyl-rifamycins, a new class of rifamycin antibiotics, are described. In these derivatives the positions 3 and 4 have been incorporated into an imidazolyl ring bearing a spiro-piperidyl group N substituted with linear and branched aliphatic chains. The in vitro antibacterial activity against Staphylococcus aureus and Mycobacterium tuberculosis increases w...

Intra and intermolecular interactions found in the developed crystals of synthesized py-ron-2,4-dione derivatives play crucial rules molecular conformations crystal stabili-ties, respectively. In this regard, Hirshfeld calculations were used to quantitatively analyze different structures some functionalized py-ran-2,4-dione derivatives. The X-ray structure pyran-2,4-dione derivative namely (3E,...

Enyne alcohols can react as precursors of either dienes or dienophiles with different substrates after hydroxylation and isomerization by gold catalysis. As such, oxa-bridged tricyclo[5.2.2.02,6]-undec-8-ene-3,5-dione derivatives have been obtained by the Diels–Alder reaction and tetrahydro-1H-furo[3,4-c]pyran derivatives could be accessed by the hetero-Diels–Alder cycloaddition.