Spindle cell carcinoma of head and neck, a subtype of squamous cell carcinoma is a unique and rare neoplasm. It has a more aggressive behavior as compared to classical squomous cell carcinoma warranting surgical interventions with wider surgical margins. Immunohistochemistry along with routine histopathology is essential in establishing the diagnosis of spindle cell carcinoma. We at Dr. B. Boro...

Hyalinizing spindle cell tumor with giant rosettes (HSCTGR) is a recently described tumor, which is regarded as an unusual variant of low-grade fibromyxoid sarcoma. Proof of a metastatic potential was lacking. The patient in the report was a 35-yr-old woman who showed multiple bilateral pulmonary nodules with massive pleural effusion in the right side. She had a history of a mass excision in th...

Desmoplastic melanoma (DM) represents a distinctive rare variant of spindle cell melanoma with a predilection for chronically sun-exposed skin of the elderly. This neoplasm is notoriously difficult to diagnose, both clinically and histopathologically. Therefore, DM is deeply infiltrative at the time of presentation. Histologically, the tumor presents as a proliferation consisting of non-pigment...

The diagnosis of cutaneous and subcutaneous spindle cell neoplasms in children is often challenging has potential therapeutic prognostic implications. Although correctly diagnosing dermatofibrosarcoma protuberans infantile fibrosarcoma paramount, pathologists should not ignore a number diagnostic pitfalls linked to mostly rare tumors with completely different clinical outcomes. In the last deca...

Superficial myofibroblastoma of the lower female genital tract is a rare benign, recently recognized neoplasm that mostly affects vulvovaginal area. In this paper we reported case 47years old lady who had 3-Normal vaginal deliveries , she presented with complain dysuria difficult micturition abdominal pain, heaviness in vagina and discharges. Vaginal examination showed well demarcated smooth ma...

Dear Dr. Bedrossian: Although histological examination is by-and-far considered the gold standard for most soft tissue diagnoses, fine needle aspiration (FNA) is an excellent modality to determine the initial characteristics of the lesion in question. To our knowledge, there have been only two reported cases of ordinary lipoma and spindle-cell lipoma occurring at the same time in the same patie...

The suppression of the regenerative chatter phenomenon in turning process via the variation of the frequency and amplitude of the spindle motor excitation is carried out in this research. A programmable inverter is employed for variable periodic excitation of the spindle motor. A set of turning experiments is designed and performed on a number of conical work pieces both in constant spindle spe...

Cutaneous Kaposi sarcoma (KS) is a vascular neoplasm with broad spectrumclinicopathology. An epithelioid morphology, rare recent variant of KS, many variants KS that may mimic other neoplasms poses diagnostic challenge. We report on 75-year-old Saudi man HIV- negative who had been diagnosed classical the right foot 8 years before present episode. Histopathological findings new lesion included a...

Spindle cell neoplasms are defined as neoplasms that consist of spindle-shaped cells in the histopathology. Spindle cell neoplasms can affect the oral cavity. In the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components. This article aims to review the spindle cell neoplasms of the oral cavity with emphasis on histopathology. ...

Primary sarcomas of the breast are rare neoplasms which comprise between 0.2%-1.0% of all breast malignancies. They often carry a poor prognosis with mortality rates greater than 40%. In addition, these malignancies can be difficult to diagnose in a timely fashion as they can mimic other benign breast pathologies such as cysts. Here we present a case of a primary spindle cell carcinoma of the b...