spinal cord injury (sci) results in up regulation and/or down regulation of several genes that may affect neuronal death and subsequent loss of motor function and also neuropathic pain. to expand a practical therapy, it is essential to recognize the specific molecular pathways altered as a function of time after spinal cord injury. this will help to develop strategies for positive manipulation ...

background & aim: patients with spinal cord injury (sci) impose a heavy burden on health care system. awareness on prevalence and incidence of sci is important because this would show the necessity of prevention. this study aimed to investigate the epidemiology and types of traumatic spinal cord injuries in a trauma referral center in guilan. methods & materials/patients: this is a descriptive ...

INTRODUCTION Previous work suggests that patients with isolated penetrating trauma rarely require spinal immobilisation. This study aimed to identify the incidence of mechanically unstable, or potentially mechanically unstable, spinal column injuries in penetrating trauma patients. The study also aimed to identify the incidence of spinal cord injury as a result of penetrating trauma in Scotland...

6 ORIGINAL PAPERS 7 ABBREVIATIONS 8 INTRODUCTION 1. Clinical background and epidemiology 9 2. Pathophysiology of spinal cord and peripheral nerve injury 2.1. Spinal cord 9 2.1.1. Acute and sub-acute spinal cord injury 10 2.1.2. Chronic spinal cord injury 11 2.2. Peripheral nerve 11 3. Regeneration following spinal cord and peripheral nerve injury 3.1. Regeneration following spinal cord injury 1...

The peripheral axonal branch of primary sensory neurons readily regenerates after peripheral nerve injury, but the central branch, which courses in the dorsal columns of the spinal cord, does not. However, if a peripheral nerve is transected before a spinal cord injury, sensory neurons that course in the dorsal columns will regenerate, presumably because their intrinsic growth capacity is enhan...

BACKGROUND Spinal injury in children is rare, and poses many difficulties in management. AIMS To ascertain the prevalence of spinal injury within the paediatric trauma population, and to assess relative risks of spinal injury according to age, conscious level, injury severity score (ISS), and associated injuries. METHODS Spine injured children were identified from the UK Trauma Audit & Rese...

: Spinal cord injury is possibly the most disruptive and traumatic event that can occurin anyone's life. It poses huge challenges in form of coping process as well rehabilitation.

Introduction Conventional magnetic resonance imaging (MRI) is the best imaging modality to demonstrate ligamentous injury, hematoma, disk herniation, spinal cord edema and hemorrhage that occur following trauma. Quantitative and qualitative image parameters like lesion length, maximum spinal cord compression, spinal cord swelling and, presence of hemorrhage within the cord has been reported to ...

In this review of neurocontrol of movement after spinal cord injury, we discuss neurophysiological evidences of conducting and processing mechanisms of the spinal cord. We illustrate that external afferent inputs to the spinal cord below the level of the lesion can modify, initiate, and maintain execution of movement in absence or partial presence of brain motor control after chronic spinal cor...

Several studies have shown the occurrence of Periodic Leg Movement (PLM) in spinal cord injury patients. The aim of this study was to identify the occurrence of limb movements during sleep in spinal cord injury rats and the possible involvement of the spinal cord in causing these movements. The animals were allocated to spinal cord injury (SCI) and SHAM groups. The two groups were submitted to ...