the influenza a virus is of global concern for the poultry industry, especially the h5 subtype as it has the potential to become highly pathogenic for poultry and mankind. recently, plant expression systems have gained interest as an alternative for the production of vaccine antigens. the goal of the present study was to investigate the possibility of expressing the ha1 protein in nicotiana tab...

The coronavirus spike protein is a multifunctional molecular machine that mediates coronavirus entry into host cells. It first binds to a receptor on the host cell surface through its S1 subunit and then fuses viral and host membranes through its S2 subunit. Two domains in S1 from different coronaviruses recognize a variety of host receptors, leading to viral attachment. The spike protein exist...

Castor is one of neglected African oil crops with little research attention in Nigeria. In the present research, eighty-six castor genotypes were evaluated at three locations in Niger State, Nigeria. The aim was to estimate the extent of genetic variability and also to examine the associations among the seed yield and its components. The treatments were laid out in an Alpha Lattice Design with ...

SARS-CoV-2 Vaccine Design A recent study of the D614G variant spike protein sheds light on a mechanism underlying relatively increased infectivity virions expressing it and has...

The murine coronavirus, mouse hepatitis virus (MHV) strain A59, causes acute encephalitis and chronic demyelinating disease as well as hepatitis in mice. The JHM strain (also called MHV-4 or JHM.SD) causes fatal encephalitis and only minimal hepatitis. Previous analysis of chimeric recombinant MHVs in which the spike gene, encoding the protein that mediates viral entry and cell-to-cell fusion, ...

toxoplasma gondii contain various immunogenic antigens. the most important toxoplasma antigens are somatic and excreted/secreted antigens. rhoptry proteins are known as excreted/secreted antigens. these antigens have been proposed as a vaccine candidate against toxoplasmosis. the main objective of the present work was cloning rhoptry protein1 (rop1) gene of toxoplasma gondii (rh) in a cloning v...

An experiment was conducted to estimate the genetic variability, heritability and advance in 100 wheat genotypes including ten parents 45 F1 F2 for obtained through half diallel mating design pea during 2021-22 at Oil Seed Farm, Kalyanpur, C.S. Azad University of Agriculture Technology, Kanpur-208002 (U.P.) Quantitative analysis were carried out all parameters which are directly or indirectly a...

Variants of Concern or Interest SARS-CoV-2 (VOC VOI), the coronavirus responsible for COVID-19, have emerged in several countries. Mutations amino acid 452 Spike protein are particularly important and associated with some these variants: L452R, present Delta VOC, L452Q, Lambda VOI. These mutations been both increased infectivity evasion protective immune response. A search on GISAID to detect n...