RNA interference (RNAi) screening is extensively used in the field of reverse genetics. RNAi libraries constructed using random oligonucleotides have made this technology affordable. However, the new methodology requires exploration of the RNAi target gene information after screening because the RNAi library includes non-natural sequences that are not found in genes. Here, we developed a web-ba...

Static transistor level timing analysis has become more and more accepted method for performance evaluation because of its reduced design cycle time when compared to the vector based timing analysis. These static timing analysis tools use transistor level delay modelling to identify timing-critical paths and estimate performance of the design. With increase in complexity of designs it becomes n...

The Steptoean Positive Isotopic Carbon Excursion (SPICE) is a prominent +4–5‰ shift in the Cambrian δ13C record used for global chronostratigraphic correlation. onset of this excursion traditionally placed at base Pterocephaliid trilobite biomere (base Furongian Series). Recent studies have documented local controls on expression SPICE and emphasize need standards these complex biogeochemical s...

The device library in the standard circuit simulator (SPICE) lacks a gallium nitride based high-electron-mobility-transistor (GaN-HEMT) model, required for design and verification of power-electronic circuits. This paper shows that GaN-HEMTs can be modeled by selected equations from MOSFET LEVEL 3 model SPICE. A method is proposed extraction SPICE parameters these equations. parameter-extractio...

Historically, simulation of transient phenomena related to power systems has been carried on using the electromagnetic transients program (EMTP) [1] or one of its variants, such as the alternative transient program (ATP) or electromagnetic transients for dc (EMTDC), which are all based on the trapezoidal integration rule and the nodal approach. These software packages use fixed-step algorithms,...

One oC the most popular and most powerCul circuit simulators, the SPICE-2G program Crom University oC California, Berkeley, is rather inefficient in interactive applications because oC its "batch-oriented" structure. SPICE-PAC is a package (or a set) oC subroutines which is Cunctionally equivalent to the SPICE-2G circuit simulator, i.e., it accepts the same circuit description and perCorms all ...

Recent years have seen significant research in finding closed form expressions for the delay of the RLC interconnect which improves upon the Elmore delay model. However, several of these formulae assume a step excitation. But in practice, the input waveform does have a non zero time of flight. There are few works reported so far which do consider the ramp inputs but lacks in the explicit nature...

The design and implementation of a component-based distributed Java front-end for the Berkeley SPICE circuit-simulation program is described. The front-end is architected as a client-server application implemented via the Remote Method Invocation (RMI) API. A graphical user-interface is implemented on the client-side which has multiple components for command and control, graphing, text-editing ...

The accurate analog simulation of critical circuit parts is a key task in the R&D process of integrated circuits. With the increasing complexity of integrated circuits it is becoming cumulatively challenging to simulate in the analog domain and within reasonable simulation time. Previous speedup approaches of the SPICE (Simulation Program with Integrated Circuit Emphasis) analog circuit simulat...

Introduction: There are two types of MOS transistors, pMOS and nMOS, which are usually employed as digital switches to implement some Boolean functions. Although the MOS transistors are treated conceptually as digital devices that have logical values either “true” or “false”, they are intrinsically analog devices whose node voltage and branch current are real numbers. Thus, in order to make bes...