To compare the role of 99mTc-MIBI SPECT-CT image and US in reoperation of persistent secondary hyperparathyroidism patients. A total of 8 persistent secondary hyperparathyroidism patients underwent parathyroidectomy. The sensitivity and accuracy of US and 99mTc-MIBI images before operation were determined. 9 of 14 surgical resection tissues from 8 persistent secondary hyperparathyroidism patien...

We prove microlocal properties of a generalized Radon transform that integrates over lines in R3 with directions parallel to a fairly arbitrary curve on the sphere. This transform is the model for problems in slant-hole SPECT and conical-tilt electron microscopy, and our results characterize the microlocal mapping properties of the SPECT reconstruction operator developed and tested by Quinto, B...

This article presents the use of Support Vector Machines (SVM) to diagnose the ischemic heart disease using heart images obtained from Single Proton Emission Computed Tomography (SPECT). The data set came from 267 different patients and was divided into several sub-sets containing training and validation data. The study consisted in comparing results of classifying cardiac SPECT images using SV...

The purpose of this study was to evaluate the effects of voxel size and iterative reconstruction parameters on the radial and tangential resolution for 99mTc SPECT as a function of radial distance from isocenter. SPECT/CT scans of eight coplanar point sources of size smaller than 1 mm3 containing high concentration 99mTc solution were acquired on a SPECT/CT system with 5/8 inch NaI(Tl) detector...

Yttrium-90 ((90)Y)-microspheres administered via the hepatic artery has been used for the treatment of unresectable primary or metastatic cancer in the liver. Prior to (90)Y therapy, however, the (90)Y administered activity and the percent shunting to lungs must be determined, most commonly by gamma camera imaging of technetium-99m ((99m)Tc)-macroaggregated albumin (MAA). The purpose of the cur...

UNLABELLED Our objective was to investigate the feasibility of subtraction for SPECT images of (99m)Tc-MIBI double-phase parathyroid scintigraphy. METHODS Fourteen patients with hyperparathyroidism were enrolled in the present study. Histopathologically, excised tissue specimens showed hyperplasia in 11 patients and adenoma in 3 patients. Both ultrasonography and (99m)Tc-sestamibi (MIBI) SPEC...

PURPOSE The aim of this article is to propose an exact SPECT region of interest (ROI) reconstruction method using truncated transmission and truncated emission data. METHODS Recently, the authors published two articles in Physics in Medicine and Biology with two results in SPECT ROI emission image reconstruction. The first result states that if the transmission data are truncated but the emis...

OBJECTIVE A novel multifocal collimator, IQ-SPECT (Siemens) consists of SMARTZOOM, cardio-centric and 3D iterative SPECT reconstruction and makes it possible to perform MPI scans in a short time. The aims are to delineate the normal uptake in thallium-201 ((201)Tl) SPECT in each acquisition method and to compare the distribution between new and conventional protocol, especially in patients with...

We have developed semi-automated and fully-automated tools for the analysis of 3D single-photon emission computed tomography (SPECT) images. The focus is on the efficient boundary delineation of complex 3D structures that enables accurate measurement of their structural and physiologic properties. We employ intensity based thresholding algorithms for interactive and semi-automated analysis. We ...

This review sets out to discuss the foremost applications of artificial intelligence (AI), particularly deep learning (DL) algorithms, in single-photon emission computed tomography (SPECT) and positron (PET) imaging. To this end, underlying limitations/challenges these imaging modalities are briefly discussed followed by a description AI-based solutions proposed address challenges. will focus o...