BACKGROUND Prior research has identified unrealistic optimism as a bias that might impair informed consent among patient-subjects in early-phase oncology trials. However, optimism is not a unitary construct; it also can be defined as a general disposition, or what is called dispositional optimism. The authors assessed whether dispositional optimism would be related to high expectations for pers...

BACKGROUND Tumor cells are known to be heterogeneous with respect to their metastatic activity, proliferation rate, and activity of several enzymes. However, little is known about the heterogeneity of tumor angiogenic activity. We investigated whether heterogeneity of angiogenic activity could be responsible for the well-known observation of "no take" of human tumors transplanted into immunodef...

BACKGROUND Rapid growth in global health activity among US medical specialty education programs has lead to heterogeneity in types of activities and global health training models. The breadth and scope of this activity is not well chronicled. METHODS Using a standardized search protocol, we examined the characteristics of US medical residency global health programs by number of programs, clin...

In this article we describe a new Hermite series based sequential estimator for the Spearman rank correlation coefficient and provide algorithms applicable in both stationary non-stationary settings. To treat setting, introduce novel, exponentially weighted correlation, which allows local nonparametric of bivariate data stream to be tracked. best our knowledge is first algorithm proposed estima...

Performance of different organizations, such as hospitals is mainly influenced by their managers' performance. Nursing managers have an important role in hospital performance and their managerial skills can improve the quality of the services. Hence, the present study was conducted in order to assess the relationship between the managerial skills and the results of their performance evaluation ...

Abstract Background Perception of entrapment can emerge when someone feels trapped in an aversive situation and incapable escape. Depression is closely related to the construct entrapment. In China, men who have sex with (MSM) a high prevalence depression; therefore, tool evaluate this population needed. We evaluated validity reliability Chinese version scale (ES) relationship depression among ...

Introduction: Non-adherence to self-care is often found in diabetes mellitus (DM) patients. Non-compliance DM patients performing can affect the quality of life This study aimed explain relationship between management and Methods: research design was analytically observational with a cross-sectional approach. The sample this 80 respondents treated at RSUD Ibnu Sina Gresik purposive sampling tec...

INTRODUCTION Rheumatoid arthritis (RA) is associated with hypogalactosylation of immunoglobulin G (IgG). We examined whether a proxy measure for galactosylation of IgG N-glycans could predict response to therapy or was differentially affected by methotrexate (MTX) or TNF blockade. METHODS Using a previously defined normal phase high-performance liquid chromatography approach, we ascertained t...