background: testosterone and its metabolites have important roles in learning and memory. the current study has conducted to assess the effect of pre-training, post-training and pre-probe trial intrahippocampal ca1 administration of 3 alpha-anderostanediol (one of the metabolites of testosterone) and indomethacin (as 3 alpha-hydroxysteroid dehydrogenase enzyme blocker) on acquisition, consolida...

ca1 region of hippocampus has an important role in learning and memory. previous reports have shown that androgens like testosterone and its metabolites are present in high concentration in ca1 region of hippocampus. androgen receptors have also high density in this region. therefore, it is suggested that neurohormones in ca1 have an important role in learning and memory. it is likely that test...

Introduction: Consumption of vitamin D3 is effective to reduce intensity of autoimmune diseases such as multiple sclerosis. Neurons of the central nervous system are constantly exposed to reactive oxygen species and these factors play a key role in the destruction of myelin and damage of axons. The hippocampus is a vital center for learning and memory in central nervous system. This area is ...

background:purpose of present study was to investigate whether chronic exposure to zinc fume would affect serum zinc levels, memory, and cognition in zinc fume-exposed workers. methods:in a cross-sectional study, all zinc fume-exposed workers (exposed, n=20) were compared with unexposed workers (reference, n=20) matched for sex and education level in a zinc galvanization factory. the workers we...

Nitric oxide (NO) is thought to be involved in spatial learning and memory in several brain areas such as hippocampus. This study examined the effects of post-training intrahippocampal microinjections of 1400W as a selective inducible nitric oxide synthase (iNOS) inhibitor on spatial memory, in both anesthetized and non-anesthetized situations in rats. In the present work, 4-day training trials...

Introduction: The N-methyl-D-aspartate (NMDA) receptors, which have been implicated in memory formation, could be noncompetitively blocked by ketamine. The present study examines the short term effect of ketamine on induction of anterograde and retrograde amnesia in male rats using Morris water maze (MWM). Methods: Male N-MRI rats were randomly divided into nine experimental groups. MWM stud...

      Diabetes mellitus is associated with disturbances of learning and memory and cognitive functioning. Aegle marmelos Corr. from Rutaceae family, is widely used in Iranian folk medicine for the treatment of diabetes mellitus. It decreases blood glucose level by improving glucose tolerance and also has lipid-lowering and antioxidant properties. Considering the beneficial antidiabetic...

This paper aims to improve locality of references by suitably choosing array layouts. We use a new definition of spatial reuse vectors that takes into account memory layout of arrays. This capability creates two opportunities. First, it allows us to develop an array restructuring framework based on a combination of hyperplane theory and reuse vectors. Second, it allows us to observe the effect ...

Objective: The present study investigates the effect of Tiliacora triandra leaf extract on spatial learning, memory, and learning flexibility as well as hippocampal choline acetyltransferase (ChAT) activity in mice.  Materials and Methods: Thirty male ICR mice were randomly divided into three groups including 10% Tween 80, T. triandra 300 mg/kg and T. triandra 600 mg/kg. All administrations wer...

Parallel applications exhibit a wide variety of memory reference patterns. Designing a memory architecture that serves all applications well is not easy. However, because tolerating or reducing memory latency is a priority in e ective parallel processing, it is important to explore new techniques to reduce memory tra c. In this paper, we describe a snoopy cache coherence protocol that uses a la...