Diabetes Mellitus is Associated With Higher Risk of Developing Decompensated Cirrhosis in Chronic Hepatitis C Patients. Saeed MJ1, Olsen MA, Powderly WG, Presti RM. J Clin Gastroenterol. 2017 Jan;51(1):70-76. GOALS: To investigate the association of diabetes with risk of decompensated cirrhosis in patients with chronic hepatitis C (CHC). BACKGROUND: Direct-acting antivirals are highly effective...

High-Dose Ribavirin Enhances Early Virological Response in Hepatitis C Genotype 1Infected Patients. Lindahl K1, Hörnfeld E, Ståhle L, Carlsson T, Weiland O, Parke Å, Schvarcz R. Ther Drug Monit. 2015 Dec;37(6):745-50. doi: 10.1097/FTD.0000000000000210. BACKGROUND: The aim of the study was to investigate whether patients with a previous nonresponse to standard of care treatment with ribavirin do...

Post-Treatment Resistance Analysis of Hepatitis C Virus from Phase 2 and 3 Clinical Trials of Ledipasvir/ Sofosbuvir. Wyles D1, Dvory-Sobol H2, Svarovskaia Doehle ES3, et al. J Hepatol. 2016 Dec 3. pii: S0168-8278(16)30699-7. doi: 10.1016/j.jhep.2016.11.022. [Epub ahead of print] BACKGROUND & AIMS: Ledipasvir/sofosbuvir combination treatment in phase 3 clinical trials, resulted in sustained vir...

Although engaging in an active lifestyle is beneficial for maintaining quality of life, a majority of wheelchair users are inactive. This study investigated the mobility characteristics and activity levels of manual wheelchair users in the residential setting and at the National Veterans Wheelchair Games (NVWG). Demographic factors that may have influenced activity in the home environment were ...

In Pay-As-You-Drive (PAYD) automobile insurance, the premium is fixed based on the distance traveled, while in usage-based insurance (UBI) the driving patterns of the policyholder are also considered. In those schemes, drivers who drive more pay a higher premium compared to those with the same characteristics who drive only occasionally, because the former are more exposed to the risk of accide...

Currently within the Canadian research landscape, patients as partners or ambassadors have become part of the fabric for research funding; “nothing about me without me” (1). My recent personal experiences at pain conferences and research team meetings as a patient partner, who is also an academic researcher, suggest we need to evolve a philosophy of engagement that serves both the patient and t...

In this paper we propose a conditional logic IBC to represent iterated belief revision. We define an iterated belief revision system by strengthening the postulates proposed by Darwiche and Pearl [3]. First, following the line of Darwiche and Pearl, we modify AGM postulates to make belief revision a function of epistemic states rather than of belief sets. Then we propose a set of postulates for...

Samira Hosseini Hooshyar, Armita Shahesmaeili, Roya Safari Faramani, Razieh Khajehkazemi, Maryam Nasirian, Hamid Sharifi, Kianoosh Kamali. HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran; Modeling in Health Research Center, Institute for Futures Studies in Health...

Roya Safari Faramani, Armita Shahesmaeili, Samira Hosseini Hooshyar, Razieh Khajehkazemi, Maryam Nasirian, Hamid Sharifi, Kianoosh Kamali. Modeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health...