Rifabutin is wide spectrum antimicrobial agent, effective in the treatment of infection caused by M. tuberculosis, avium and Leprae also used multidrug resistant TB. very poorly water soluble drug (0.19mg/ml) with high permeability. For enhancement solubility a hydrophobic has significant role development liquid dosages form. The main purpose this study was to improve co solvency method. Differ...

In this paper, we present a new time series model, which describes self-exciting threshold autoregressive (SETAR) nonlinearity and seasonality simultaneously. The model is termed multiplicative seasonal SETAR (SEASETAR). It can be viewed as a special case of a general non-multiplicative SETAR model by imposing certain restrictions on the parameters of the latter model. Related to these restrict...

Let X = G/B and let L1 and L2 be two line bundles on X. Consider the cup product map H1 (X,L1)⊗H q2 (X,L2) → H (X,L), where L = L1⊗L2 and q = q1+q2. We find necessary and sufficient conditions for this map to be a nonzero map of G–modules. We also discuss the converse question, i.e. given irreducible G–modules U and V , which irreducible components W of U⊗V may appear in the right hand side of ...