AIM To determine in vivo, the degree of microbial reduction after chemo-mechanical preparation of human root canals containing necrotic pulp tissue when using two endodontic irrigating reagents, sodium hypochlorite (NaOCl) or chlorhexidine gel (CHX). METHODOLOGY Thirty-two single rooted teeth with necrotic pulp were divided into two groups. One group (n=16) was irrigated with 2.5% NaOCl, whil...

The aim of this study was to analyze the effectiveness of 5.25% sodium hypochlorite (NaOCI) in preventing inoculation of periapical tissues with contaminated patency files. Twenty-eight extracted human permanent teeth with single canals were used in the study. Group I teeth were filled with NaOCl, and #15 stainless steel files contaminated with Streptococcus sanguis (ATCC #10556) were allowed t...

PURPOSE The aim of this study was to compare the effects of different denture cleansers on the surface roughness and microhardness of various types of posterior denture teeth. MATERIALS AND METHODS 168 artificial tooth specimens were divided into the following four subgroups (n=42): SR Orthotyp PE (polymethylmethacrylate); SR Orthosit PE (Isosit); SR Postaris DCL (double cross-linked); and SR...

Both hypochlorite and ionizing radiation induce oxidation processes of biomolecules. The effects are dependent to a large degree on the dose of the oxidizing agent. Previously we observed that split doses of gamma radiation caused lower hemolysis than the same but single doses. The critical factors influencing the occurrence of this effect were: the value of the first dose and the time between ...

The purpose of this study was to quantify the volume of 17% ethylene diamine tetra-acetic acid (EDTA) needed to efficiently remove the smear layer after rotary instrumentation, and to determine if additional irrigation has any effect on debris removal. Forty single canal teeth were instrumented with ProFile GT rotary instruments. Experimental groups were irrigated with 1, 3, or 10 ml of 17% EDT...

The purpose of the review was to assess the effect of root canal irrigants on dentin bonding. A PubMed-based search was conducted on the articles published from 1980 to 2016. A brief overview and reviewing the effect on dentin bonding of common root canal irrigation solutions such as sodium hypochlorite (NaOCl), chlorhexidine (CHX), ethylenediaminetetraacetic acid (EDTA), mixture of a tetracycl...

background: multi-specie biofi lms are highly resistant to antimicrobials due to cellular interactions found in them. the purpose of this study was to evaluate, by confocal laser scanning microscopy, the biofi lm dissolution effectiveness of different irrigant solutions on biofi lms developed on infected dentin in situ. materials and methods: a total of 120 bovine dentin specimens infected intr...

introduction: the aim of this study was to compare the antimicrobial effects of mtad, sodium hypochlorite (naocl) and their combination on endodontic micro-organisms. materials and methods: zone of inhibition (zi) and minimum inhibitory concentration (mic) were the techniques used. in zi technique blood agar plates were inoculated with organisms, paper discs were soaked with irrigants and maxim...

The purpose of this study was to compare the reaction of rat subcutaneous connective tissue to 0.9% sterile saline, 2.5% sodium hypochlorite (NaOCl), 5.25% NaOCl and 2% chlorhexidine gluconate solution or gel. Six circles were demarcated on the dorsal skin of 24 male Wistar rats, leaving 2 cm between each circle. Using a syringe, 0.1 mL of each root canal irrigant was injected subcutaneously in...

The 2014 West African Ebola virus disease outbreak was the largest to date, and conflicting, chlorine-based surface disinfection protocols to interrupt disease transmission were recommended. We identified only one study documenting surface disinfection efficacy against the Ebola virus, showing a >6.6 log reduction after 5-minute exposure to 0.5% sodium hypochlorite (NaOCl) based on small-scale ...