THE methods employed for the estimation of pyruvic acid are largely based upon the reaction of its carbonyl group with phenylhydrazine. Its estimation in complex biological fluids where there are other compounds which react likewise is therefore difficult and, particularly when pyruvic acid exists in small quantities amidst these compounds, the estimation is unreliable even when controls are ru...

BACKGROUND Hexavalent Chromium (Cr (VI)) compounds are extremely toxic and have been demonstrated to induce nephrotoxicity associated with oxidative stress in humans and animals. The wide environmental distribution of these agents lead to an increase interest of preventive effects of its adverse effects. OBJECTIVES The propose of the present study was to determine the potential protective eff...

A potentiometric titration method for the determination of minoxidil based on its redox reaction with K2Cr2O7 is described. The best results were observed using 1.00 x 10-3 mol L-1 K2Cr2O7 and 1.00 x 10-2 mol L-1 minoxidil solutions, and the minoxidil as titrant in 2.00 mol L-1 H2SO4 medium. The method was applied to commercial samples and compared with the results from a chromatographic proced...

BACKGROUND The oral mucosa is constantly exposed to several irritants and allergens including dental materials, but the role of contact allergy in oral disease is obscure. OBJECTIVE To analyze positive patch test results in patients with oral diseases and evaluate the clinical relevance of oral diseases with contact allergy to dental materials. METHODS We retrospectively analyzed patch test...

The in vivo binding of chromium to whole chromatin, polynucleosomes, DNA, and cytoplasmic RNA-protein fraction from liver and kidney was examined after treatment of rats with sodium dichromate and chromium(III) chloride. Significant amounts of chromium were bound to DNA and the nonhistone proteins of chromatin and to cytoplasmic RNA-protein fraction. The binding of chromium to the nuclear and c...

BACKGROUND The increasing use of herbal drugs and their easy availability have necessitated the use of mutagenicity tests to analyze their toxicity and safety. OBJECTIVES The aim of this study was to determine the in vitro mutagenicity of Artemisia draconculus L., a herbal drug, by performing single cell gel electrophoresis (SCGE). MATERIALS AND METHODS In this study, we obtained a herbal d...

BACKGROUND The irritant sodium lauryl sulfate (SLS) is known to cause a decrease in the stratum corneum level of natural moisturizing factor (NMF), which in itself is associated with changes in corneocyte surface topography. OBJECTIVE To explore this phenomenon in allergic contact dermatitis. METHODS Patch testing was performed on patients with previously positive patch test reactions to po...

The title compound, C(20)H(18)O(6), has been synthesized from 4-methoxy-phenyl 3-O-benzo-yloxy-α-l-rhamnopyran-oside by oxidation on treatment with pyridinium dichromate in the presence of acetic anhydride. In the mol-ecule, the pyran ring adopts an envelope conformation with the O atom at the flap position. Weak inter-molecular C-H⋯O hydrogen bonding is present in the crystal structure.

Nicotinium dichromate (NDC) oxidation of pentaamminecobalt (III) complexes of ∝ hydroxy acids in micellar medium yielding nearly 100% of keto acid complex is ultimate product. The decrease in UV-Visible absorbance at 502 nm for Co(III) complex corresponds to nearly 0% reduction of the initial absorbance. The stoichiometry of unbound ligand and cobalt(III) complex is accounting for no reduction ...