Objective: A novel, simple, precise, accurate, sensitive, and reproducible HPLC method for determining clopidogrel bisulfate in Wistar rat plasma was developed validated. Methods: The chromatographic separation performed using Xterra C18 (250 x 4.6 mm, 5?) column. Mobile phase composed of Acetonitrile ACN: 0.05M potassium dihydrogen orthophosphate buffer pH 4.2 the ratio 75:25% v/v at a flow ra...

In this review, we elucidate the central role played by fossil fuel combustion in health-related effects that have been associated with inhalation of ambient fine particulate matter (PM2.5). We especially focus on individual properties and concentrations metals commonly found PM air pollution, as well their sources adverse health effects, based both epidemiologic toxicological evidence. It is k...

[1] The partitioning between solid and aqueous phases of tropospheric sulfate-ammonium particles is simulated with a global 3-D chemical transport model (CTM). The simulation explicitly accounts for the hysteresis of particle phase transitions by transporting aqueous sulfate and three solid sulfate forms (namely, ammonium sulfate, letovicite, and ammonium bisulfate). Composition-dependent deliq...

Organosulfates are components of secondary organic aerosols (SOA) that form from oxidation of volatile organic compounds (VOCs) in the presence of sulfate. In this study, the composition and abundance of organosulfates were determined in fine particulate matter (PM2.5) collected from Centreville, AL, during the Southern Oxidant and Aerosol Study (SOAS) in summer 2013. Six organosulfates were qu...

Atmospheric particles containing organic species and inorganic salts may undergo liquid–liquid phase separation when the relative humidity varies between high and low values. To better understand the parameters that affect liquid–liquid phase separation in atmospheric particles, we studied the effects of molecular weight and temperature on liquid–liquid phase separation in particles containing ...

The effect of aqueous versus crystalline sulfatenitrate-ammonium tropospheric particles on global aerosol direct radiative forcing is assessed. A global threedimensional chemical transport model predicts sulfate, nitrate, and ammonium aerosol mass. An aerosol thermodynamics model is called twice, once for the upper side (US) and once for lower side (LS) of the hysteresis loop of particle phase....

Periana et al. [Science 1998, 280, 560] previously reported two catalysts for lowtemperature methane activation to methanol: PtCl2(NH3)2 and PtCl2(bpym). It was shown that the ammine catalyst is much more active, but it decomposes rapidly in sulfuric acid to form a PtCl2 precipitate, while the bpym system is long-lived. To have a basis for developing new catalysts that would not decompose, we u...