The prognosis for adult T cell leukemia/lymphoma (ATL) is very poor, and only allogeneic hematopoietic stem cell transplantation (allo-SCT) has been considered to be a curative treatment for ATL. In this study, we retrospectively analyzed data for patients who had received allo-SCT for ATL in Hokkaido, the northernmost island of Japan, to determine prognostic factors. Fifty-six patients with a ...

The mechanism for OH and NO3 radical-initiated oxidation reactions of methyl methacrylate (MMA) was investigated by using density functional theory (DFT) molecular orbital theory. Geometrical parameters of the reactants, intermediates, transition states, and products were fully optimized at the B3LYP/6-31G(d,p) level. Detailed oxidation pathways were presented and discussed. The rate constants ...

Socioculturalists are divided on two of the foundational theoretical claims of the paradigm: a process ontology of the social world; and the inseparability of the individual and the group. A process ontology holds that only processes are real; entities, structures or patterns are ephemeral and do not really exist. Inseparability is the claim that the individual and the social cannot be methodol...

Parental acceptance-rejection theory (PARTheory) is an evidence-based theory of socialization and lifespan development that attempts to predict and explain major causes, consequences, and other correlates of interpersonal—especially parental—acceptance and rejection within the United States and worldwide (Rohner, 1986, 2004; Rohner and Rohner, 1980). It attempts to answer five classes of questi...

While research findings regarding learning are somewhat mixed, early indications are encouraging and suggest sociocultural learning is useful in improving student learning under certain situations. It is suggested that future research efforts may be enhanced by more closely linking research to theory, building on the research from the field of education, and developing appropriate instruments t...

Background Stem cell units (SCUs) that are cryopreserved prior to both autologous and allogeneic hematopoietic stem cell transplants (for donor lymphocyte infusion) remain unused or partially used several times, and become an increased burden to blood banks/SCU repositories. Because of the scarcity of data regarding the duration for which the storage is useful, there is no general consensus reg...

BACKGROUND AND OBJECTIVES Many African Americans (AA) have both sickle cell trait (SCT) and diabetes mellitus. The objective of this study was to determine whether individuals with diabetes mellitus and SCT have higher rates of microvascular complications relative to those without SCT. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This was a retrospective study comparing albuminuria, estimate...

OBJECTIVE To estimate the impact of the mandatory National Collegiate Athletic Association (NCAA) sickle cell trait (SCT) screening policy on the identification of sickle cell carriers and prevention of sudden death. DATA SOURCE We used NCAA reports, population-based SCT prevalence estimates, and published risks for exercise-related sudden death attributable to SCT. STUDY DESIGN We estimate...