Introduction: Colon cancer is known as one of the most current cancers in the world and Iran that high percentage of deadly caners in the world is related to colon cancer. The use of new method to treat and control of colon cancer in developed societies are on rise. Ozone is used as the new and effective method to treat of different diseases, infections and scars. In this study, the effects of ...

To test the hypothesis that AA transporter transcripts are present in the large intestine and similarly expressed along the intestinal tract, mRNA abundance of candidate AA transporter genes solute carrier (SLC) family 7, member 9 (SLC7A9), SLC7A1, SLC7A8, and SLC43A1 encoding for b(0,+)-type AA transporter (b(0,+)AT), cationic AA transporter-1 (CAT-1), L-type AA transporter-2 (LAT-2), and L-ty...

BACKGROUND Gastrointestinal (GI) disturbances are often reported by long distance runners and are more common in women, particularly after prolonged high intensity exercise. OBJECTIVES To determine whether these symptoms could be associated with alterations in GI motility. METHODS Small bowel and colonic transit were measured using pH telemetry in a group of 11 female athletes (age 22 to 53...

Colon cancers have been shown to develop after accumulation of multiple genetic and epigenetic alterations with changes in global gene expression profiles, contributing to the establishment of widely diverse phenotypes. Transcriptional and posttranscriptional regulation of gene expression by small RNA species, such as the small interfering RNA and microRNA and the RNA-induced silencing complex ...

Koyama, Yu, Tadashi Yamamoto, Tatsuo Tani, Kouei Nihei, Daisuke Kondo, Haruko Funaki, Eishin Yaoita, Katsutoshi Kawasaki, Nobuaki Sato, Katsuyoshi Hatakeyama, and Itaru Kihara. Expression and localization of aquaporins in rat gastrointestinal tract. Am. J. Physiol. 276 (Cell Physiol. 45): C621–C627, 1999.—A family of water-selective channels, aquaporins (AQP), has been demonstrated in various o...

Colon cancers have been shown to develop after accumulation of multiple genetic and epigenetic alterations with changes in global gene expression profiles, contributing to the establishment of widely diverse phenotypes. Transcriptional and posttranscriptional regulation of gene expression by small RNA species, such as the small interfering RNA and microRNA and the RNA-induced silencing complex ...

The Wnt/β-catenin pathway plays multiple and diverse roles in development by regulating gene expression via T-cell factor/Lymphoid enhancer-binding factor (Tcf/Lef) DNA binding factors. Misregulation of this pathway is thought to initiate colon adenoma formation. It is controversial whether Tcf4 (Tcf7L2) functions as an oncogene or tumor suppressor gene in colon carcinogenesis. We show here tha...

A 57-year-old man with chronic kidney disease and a history of using numerous herbal medications visited Inje University Ilsan Paik Hospital for abdominal pain and vomiting. An abdominal radiograph showed diffuse small bowel distension containing multiple air-fluid levels and extensive calcifications along the colon. Computed tomography showed colon wall thickening with diffuse calcification al...

Genetic events, such as gene deletion, mutation, and amplification, are involved in the development and progression of colonic neoplasia. The importance of interactions between immune cells and neoplastic cells in influencing the pathogenesis of colon cancer is suggested by the clinical efficacy of levamisole, an immunostimulant, in the treatment of colon cancer and by the association of local ...