نتایج جستجو برای: slc26a4

تعداد نتایج: 451  

2015
Ying Chen Zhentao Wang Zhaoyan Wang Dongye Chen Yongchuan Chai Xiuhong Pang Lianhua Sun Xiaowen Wang Tao Yang Hao Wu Francesc Palau

The mutation spectrum of deafness genes may vary in different ethnical groups. In this study, we investigated the genetic etiology of nonsyndromic deafness in four consanguineous and two multiplex Uyghur families in which mutations in common deafness genes GJB2, SLC26A4 and MT-RNR1 were excluded. Targeted next-generation sequencing of 97 deafness genes was performed in the probands of each fami...

Journal: :Brain and language 2005
Arhonto Terzi Spyridon Papapetropoulos Elias D Kouvelas

The present study investigates the production of regular and irregular verbs in the past tense and the comprehension of passive sentences by Greek-speaking PD patients, and compares their behavior to that of normal speakers. Although the two groups manifest large scale differences at all the above constructions, the behavior of PDs is not different at regular vs. irregular past tense formation ...

Journal: :Aging & mental health 2015
Bernadette M Willemse Murna Downs Lonneke Arnold Dieneke Smit Jacomine de Lange Anne Margriet Pot

OBJECTIVES The aim of this study is to explore the extent to which staff-resident interactions address or undermine residents' psychological needs and how such interactions are associated with residents' well-being. METHOD Data on staff-resident interactions and residents' well-being were collected for 51 residents from nine long-term care settings using dementia care mapping (DCM). DCM yield...

Journal: :Pediatrics 2013
Brian C Drolet Sarah B Whittle Mamoona T Khokhar Staci A Fischer Adam Pallant

OBJECTIVES To determine pediatric program director (PD) approval and perception of changes to resident training and patient care resulting from 2011 Accreditation Council for Graduate Medical Education (ACGME) Common Program Requirements. METHODS All US pediatric PDs (n = 181) were identified from the ACGME. Functional e-mail addresses were identified for 164 (90.6%). Three individualized e-m...

2016
Giulia Gorrieri Paolo Scudieri Emanuela Caci Marco Schiavon Valeria Tomati Francesco Sirci Francesco Napolitano Diego Carrella Ambra Gianotti Ilaria Musante Maria Favia Valeria Casavola Lorenzo Guerra Federico Rea Roberto Ravazzolo Diego Di Bernardo Luis J. V. Galietta

Goblet cell hyperplasia, a feature of asthma and other respiratory diseases, is driven by the Th-2 cytokines IL-4 and IL-13. In human bronchial epithelial cells, we find that IL-4 induces the expression of many genes coding for ion channels and transporters, including TMEM16A, SLC26A4, SLC12A2, and ATP12A. At the functional level, we find that IL-4 enhances calcium- and cAMP-activated chloride/...

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