Elegant preclinical studies showed that T-cell immune synapse dysfunction in follicular lymphoma (FL) can be “repaired” with lenalidomide. Tumor-infiltrating T cells from FL patients had significant reduction in formation of the F-actin immune synapse vs healthy donor cells. Lenalidomide reversed these abnormalities by enhancing the immune synapse, an important finding also demonstrated in chro...

We consider separably closed fields of characteristic p > 0 and fixed Imperfection degree as modules over a skew polynomial ring. We axlotnatlze the correspondltlg theory and ue show that i t is complete and that ~t adnilts quantifier e l ~ n i ~ n a t ~ o n In the usual nlodule language augmented with additwe functions whlch are the analog of the p-component functions. $

The main ‘philosophical’ outcome of this article is to demonstrate that the structural description of residuated lattices requires the use of the co-residuated setting. A construction, called skew symmetrization, which generalizes the well-known representation of an ordered Abelian group obtained from the positive (or negative) cone of the algebra is introduced here. Its definition requires lea...

Let V be a vector space over a field F. The characteristic p of F is large if either p = 0 or p > dim V. When F is of large characteristic, the following questions, as well as their infinitesimal versions, are answered in this paper. Given an invertible linear map T : V → V, when does the vector space V admit a T -invariant non-degenerate symmetric (resp. skew-symmetric) biliner form? An elemen...

An association scheme is amorphous if it has as many fusion schemes as possible. Symmetric amorphous schemes were classified by A. V. Ivanov [A. V. Ivanov, Amorphous cellular rings II, in Investigations in algebraic theory of combinatorial objects, pages 39–49. VNIISI, Moscow, Institute for System Studies, 1985] and commutative amorphous schemes were classified by T. Ito, A. Munemasa and M. Yam...

We consider regularization of the parameters in multivariate linear regression models with the errors having a multivariate skew-t distribution. An iterative penalized likelihood procedure is proposed for constructing sparse estimators of both the regression coefficient and inverse scale matrices simultaneously. The sparsity is introduced through penalizing the negative log-likelihood by adding...

Consider options on a nonnegative underlying random variable with arbitrary distribution. In the absence of arbitrage, we show that at any maturity T , the large-strike tail of the Black-Scholes implied volatility skew is bounded by the square root of 2|x|/T , where x is log-moneyness. The smallest coefficient that can replace the 2 depends only on the number of finite moments in the underlying...

Let T = [0, 1) be the additive group of real numbers modulo 1, α ∈ T be an irrational number and t ∈ T. We consider skew product extensions of irrational rotations by Z 2 determined by T : T × Z 2 → T × Z 2 T (x, s 1 , s 2) = " x + α, s 1 + 2χ [0, 1 2) (x) − 1, s 2 + 2χ [0, 1 2) (x + t) − 1 «. We study ergodic components of such extensions and use the results to display irregularities in the un...

Abstract In this note, we provide a short proof of Theorem 4.3 in the paper titled Crystals, semistandard tableaux and cyclic sieving phenomenon , by Y.-T. Oh E. Park, which concerns on semi-standard Young tableaux. We also extend their result to skew shapes.

In this paper, likelihood-based inference and bias correction based on Firth’s approach are developed in the modified skew-t-normal (MStN) distribution. The latter model exhibits a greater flexibility than skew-normal (MSN) distribution since it is able to heavily skewed data thick tails. addition, tails controlled by shape parameter degrees of freedom. We provide density new present some its m...