REFERENCES 1. D Fleming, K Cross, M Barley. Recent changes in the prevalence of diseases presenting for health care. Br J Gen Pract 2005; 55: 589–595. 2. Arora SK, McFarlane SI. The case for low carbohydrate diets in diabetes management. Nutr Metab (Lond) 2005; 2: 16. 3. Kennedy RL, Chokkalingam K, Farshchi HR. Nutrition in patients with type 2 diabetes: are lowcarbohydrate diets effective, saf...

BACKGROUND Negatively-charged polyhedral boron clusters can be easily halogenated with highly stable boron-halogen bonds and are promising in radionuclide diagnostics and cancer therapy. MATERIALS AND METHODS The radio-iodination conditions for the closo-dodecaborate anion and for the conjugation of its labeled isothiocyanatobenzylammonio derivative to the monoclonal antibody (mAb) were optim...

Receptor for Advanced Glycation End Products (RAGE) is an oncogenic trans-membranous receptor overexpressed in various human cancers. However, the role of RAGE in breast cancer development and proliferation is still unclear. In this study, we demonstrated that RAGE expression levels are correlated to the degree of severity of breast cancer. Furthermore, there is a decrease in the proliferation ...

Fractal morphometry was used to investigate the ultrastructural features of the plasma membrane, perinuclear membrane and nuclear chromatin in SK-BR-3 human breast cancer cells undergoing apoptosis. Cells were incubated with 1 microM calcimycin (A23187) for 24 h. Cells in the early stage of apoptosis had fractal dimension (FD) values indicating that their plasma membranes were less rough (lower...

1. Querings K, Starz H, Balda BR. Clinical spectrum of cutaneous Langerhans’ cell histiocytosis mimicking various diseases. Acta Derm Venereol 2006;86:39-43. 2. Stein SL, Paller AS, Haut PR, Mancin AJ. Langerhans cell histiocytosis presenting in the neonatal period: A retrospective case series. Arch Pediatr Adolesc Med 2001;155:778-83 3. Punia RS, Bagai M, Mohan H, Thami GP. Langerhans cell his...

The halide perovskites have truly emerged as efficient optoelectronic materials and show the promise of exhibiting nontrivial topological phases. Since bandgap is deterministic factor for these quantum phases, here we present a comprehensive electronic structure study using first-principle methods by considering nine inorganic CsBX$_3$ (B = Ge, Sn, Pb; X Cl, Br, I) in their three structural pol...

Purpose: To elucidate the effect of leonurine on proliferation, invasion, migration, and angiogenetic potential breast cancer cells. Methods: Human cell line (MDA-MB-231) normal line, (SK-BR-3) were cultured. Both lines treated with 200, 400, or 800 μM cultured for 0 (control), 24, 48, 72 h. Cell counting kit-8 (CCK8) colony formation assays performed to measure viability proliferation. Invasio...

The goal of this study was to develop near-infrared (NIR) resonant gold-gold sulfide nanoparticles (GGS-NPs) as dual contrast and therapeutic agents for cancer management via multiphoton microscopy followed by higher intensity photoablation. We demonstrate that GGS-NPs exposed to a pulsed, NIR laser exhibit two-photon induced photoluminescence that can be utilized to visualize cancerous cells i...